Evidence map›Paper›PMID 40032735›Full record

ArticleAnnals of surgical oncology2025

Trends and Predictors of Palliative Therapy Use in Young Adults with Advanced Gastrointestinal Cancer: A National Cancer Database Study.

Olivia Monton, Kimberly Kopecky, Andrei Gurau, Orly N Farber, Elizabeth J Lilley, Jonathan B Greer, Fabian M Johnston

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Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Olivia MontonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kimberly KopeckyDivision of Surgical Oncology, Department of Surgery, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL, USA.
Andrei GurauDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Orly N FarberDepartment of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Elizabeth J LilleyDepartment of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Jonathan B GreerDepartment of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Fabian M JohnstonDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA. fajohnst@wakehealth.edu.ORCID http://orcid.org/0000-0002-2794-7179

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundYoung adults (YAs) with advanced gastrointestinal (GI) cancer have unique care needs, which may be addressed through palliative therapy.

objectivesThe aims of this study were to describe temporal trends and identify predictors of palliative therapy utilization in YAs with advanced GI cancer.

methodsWe conducted a retrospective cohort study using the National Cancer Database. YAs (18-39 years of age) diagnosed with advanced GI cancer from 2004 to 2020 were identified. We performed a trend analysis followed by univariable and multivariable logistic regression analyses.

resultsA total of 43,616 YAs with advanced GI cancer were identified, of whom 3820 (8.76%) were treated with palliative therapy. The proportion of patients who received palliative therapy increased significantly, from 5.33% in 2004 to 12.36% in 2020 (p

conclusionsPalliative therapy utilization in YAs with advanced GI cancer increased significantly over the study period, however major gaps remain in the provision of this care. Further work is needed to understand the barriers to access among YAs.

Indexed as

Gastrointestinal NeoplasmsPalliative CareAdolescentAdultDatabases, FactualFemaleFollow-Up StudiesHumansMalePrognosisRetrospective StudiesUnited StatesYoung AdultGastrointestinal cancerPalliative carePalliative therapyYoung adults

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