ArticleOpen heart2025
Patterns of systolic blood pressure response at the end of exercise and mortality and morbidity in patients referred for exercise testing.
Article in Open heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Relationship Between Right Ventricular Function and Chronotropic Incompetence in Pulmonary Arterial Hypertension Associated With Connective Tissue Disease.CHEST pulmonary · 2026Article
- Determinants and prognostic value of blood pressure trajectories during graded exercise.European journal of applied physiology · 2026Article
- Integrating Cardiopulmonary Exercise Testing in the Assessment of Aortic Stenosis: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2026Review
- The shape of the systolic blood pressure response during graded exercise: methodology, correlates and predictive value.Journal of human hypertension · 2026Observational
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPeak exercise systolic blood pressure (SBP) is associated with future cardiovascular disease (CVD) and mortality. We aimed to evaluate the predictive value of different SBP patterns at the end of exercise with these outcomes.
methodsWe studied 6329 adults (45% women) referred for exercise testing, with test duration of 6-14 min, maximal effort and valid SBP measurements at the end of exercise. The two last SBPs were indexed to work rate (mmHg/Watt), defining responses as:
resultsThe prevalence of SBP responses at the end of exercise were drop (1.1%), plateau (15.0%), slow (30.4%), intermediate (25.2%) and steep increase (28.3%). Follow-up was 8.8±3.4 years. Compared with a slow increase, the adjusted all-cause mortality risks were not statistically different for a drop (HR 1.16 (0.50-2.65)), plateau (HR 1.19 (0.85-1.66)), intermediate (HR 1.24 (0.93-1.66)) or steep SBP increase (HR 1.16 (0.89-1.52)). CVD risk was increased in those with a SBP drop (HR 3.10 (1.85-5.19), but not significantly for plateau (HR 1.17 (0.92-1.48)), intermediate or steep SBP increases (HRs 0.99-1.00).
conclusionSubjects with a slow SBP increase at the end of exercise tended to have the lowest mortality risk, although no SBP response pattern predicted all-cause mortality independently. CVD risk was strongly increased in patients with a drop in SBP and tended to be increased (non-significantly) also in patients with a plateau in SBP at the end of exercise, in comparison with increasing SBP.
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