Evidence map›Paper›PMID 40032395›Full record

ArticleBMJ open2025

Randomised controlled trial of LGBTQ-affirmative cognitive-behavioural therapy for sexual minority women's minority stress, mental health and hazardous drinking: Project EQuIP protocol.

John Pachankis, Danielle Chiaramonte, Jillian R Scheer, Hadley Ankrum, Benjamin Eisenstadt, Rebekah Hobbs, Hunter Baldwin, Jeremy D Kidd, Katie Witkiewitz, Denise Ann Esserman and 3 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05509166 (A Unified Protocol to Address Sexual Minority Women's Minority Stress, Mental Health and Hazardous Drinking), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05509166 narecruitingnot on this map

A Unified Protocol to Address Sexual Minority Women's Minority Stress, Mental Health and Hazardous Drinking

TypeinterventionalSponsorYale UniversityRan2023 to 2027Enrolled274ConditionsHeavy Drinking, Mental Health IssueArmsLGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

John PachankisDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA john.pachankis@yale.edu.ORCID http://orcid.org/0000-0002-2015-9225
Danielle ChiaramonteDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA.
Jillian R ScheerSyracuse University, Syracuse, New York, USA.
Hadley AnkrumDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA.
Benjamin EisenstadtDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA.
Rebekah HobbsDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA.
Hunter BaldwinDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, Connecticut, USA.
Jeremy D KiddColumbia University Irving Medical Center, New York, New York, USA.
Katie WitkiewitzUniv New Mexico, Albuquerque, New Mexico, USA.
Denise Ann EssermanDepartment of Biostatistics, Yale University School of Public Health, New Haven, Connecticut, USA.
Kendra PlourdeDepartment of Biostatistics, Yale University School of Public Health, New Haven, Connecticut, USA.ORCID http://orcid.org/0000-0001-6654-0710
Laurie DrabbleSan Jose State University, San Jose, California, USA.
Tonda HughesColumbia University School of Nursing, New York, New York, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
A unified protocol to address sexual minority women's minority stress, mental health and hazardous drinkingR01AA029088 · NIAAA · YALE UNIVERSITY · PI John Edward Pachankis · 2022 to 2026
$3.7M
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS R01 AA029088
6 · The paper itself

Abstract

introductionSexual minority women represent one of the highest-risk groups for hazardous drinking and comorbid mental health problems (eg, depression, anxiety). Research has identified cognitive (eg, expectations of rejection), affective (eg, emotion dysregulation) and behavioural (eg, avoidant coping) pathways through which minority stress (eg, stigma) places sexual minority women at disproportionate risk of hazardous drinking and comorbid depression/anxiety; yet no evidence-based interventions have been tested to address these pathways in this population. This article describes the design of Project EQuIP (Empowering Queer Identities in Psychotherapy), a randomised controlled trial of a transdiagnostic lesbian, gay, bisexual, transgender, queer (LGBTQ)-affirmative cognitive-behavioural therapy intervention (CBT) designed to improve minority stress coping and reduce sexual minority women's hazardous drinking and mental health comorbidities. METHODS AND ANALYSIS: This two-arm randomised controlled trial, funded by the National Institute on Alcohol Abuse and Alcoholism, has two objectives: (1) test the efficacy of 10 sessions of LGBTQ-affirmative CBT compared with 10 sessions of supportive counselling for sexual minority women in the community (anticipated n=450) who report hazardous alcohol use and meet criteria for a ETHICS AND DISSEMINATION: The Yale University Human Subjects Committee reviewed and approved the research protocol. Results of this study will be disseminated to researchers and practitioners through peer-review publications and conference presentations, and directly to study participants. TRIAL REGISTRATION NUMBER: Registered on 17 August 2022 (ClinicalTrials.gov identifier: NCT05509166).

Indexed as

AlcoholismCognitive Behavioral TherapySexual and Gender MinoritiesStress, PsychologicalAdaptation, PsychologicalAdultAnxietyDepressionFemaleHumansMental HealthRandomized Controlled Trials as TopicMENTAL HEALTHPsychosocial InterventionPUBLIC HEALTH

Identifiers

PMID40032395
PMCPMC11877267

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.