Observational studyBMJ open2025
Unravelling the trajectory of frailty and its influencing factors in elderly patients with coronary heart disease after percutaneous coronary intervention: protocol for a cohort study in China.
Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFrailty is an important factor affecting the short-term and long-term outcomes of elderly patients with coronary heart disease (CHD) after surgery. Most previous studies only assessed frailty before surgery or at discharge, and there was limited tracking of the occurrence and progression of frailty during hospitalisation and after surgery. This paper describes the trends and influencing factors of frailty in elderly patients with CHD before and 6 months after percutaneous coronary intervention (PCI). METHOD AND ANALYSIS: The frailty study is an observational, prospective cohort study aiming to recruit patients with CHD over 60 years of age who intend to undergo PCI. This study aims to investigate the evolving trends in frailty among elderly patients who have undergone PCI in the 6 months following hospital discharge. Additionally, the influence of cognitive, behavioural, psychosocial, physiological and biological factors on the trajectory of frailty changes in this population was explored based on the International Classification of Functioning, Disability and Health. There will be 11 data collection points, within 48 hours after admission, at hospital discharge and then monthly for the first 6 months, followed by assessments at 12, 24 and 36 months postdischarge. A general estimation equation will be used to analyse the overall trend of frailty. Growth mixture modelling and latent class growth modelling will both be used to identify distinct frailty trajectories. Univariate and logistic regression analyses will be used to identify predictors of trajectories. The Cox proportional hazard regression model will be employed to explore the relationship between the changing trend of different types of frailty within 6 months after discharge and survival status at 36 months. ETHICS AND DISSEMINATION: Ethical approval has been obtained from the Ethics Committee of Guangzhou First People's Hospital (K-2023-136-01). All findings will be disseminated through publication in peer-reviewed scientific journals and presentation at conferences and stakeholder organisation events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.