Evidence map›Paper›PMID 40030029›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice.

Yuki Kaneda, Yonggang Lu, Jiang Sun, Keisuke Shimada, Chihiro Emori, Taichi Noda, Takayuki Koyano, Makoto Matsuyama, Haruhiko Miyata, Masahito Ikawa

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuki Kaneda *Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.ORCID 0000-0001-6300-4234
Yonggang Lu *Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.ORCID 0000-0003-0198-8906
Jiang Sun *Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.
Keisuke ShimadaDepartment of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.ORCID 0000-0003-3739-7163
Chihiro EmoriDepartment of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.
Taichi NodaDepartment of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.ORCID 0000-0003-0260-7861
Takayuki KoyanoDivision of Molecular Genetics, Shigei Medical Research Institute, Okayama 7010202, JAPAN.ORCID 0000-0003-1675-2525
Makoto MatsuyamaDivision of Molecular Genetics, Shigei Medical Research Institute, Okayama 7010202, JAPAN.ORCID 0000-0003-2606-059X
Haruhiko MiyataDepartment of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.ORCID 0000-0003-4758-5803
Masahito IkawaDepartment of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.ORCID 0000-0001-9859-6217

Funding

Targeting sperm-specific proteins during meiosis and sperm morphogenesisP01HD087157 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MATZUK, MARTIN M. · 2017 to 2021
$6.2M
Functional analysis of novel testis-expressed secreted and transmembrane proteinsR01HD088412 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MARTIN M. MATZUK · 2016 to 2026
$4.5M
Gates Foundation INV-001902HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) P01HD087157HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R01HD088412MEXT | Japan Society for the Promotion of Science (JSPS) JP19H05750MEXT | Japan Society for the Promotion of Science (JSPS) JP21H04753MEXT | Japan Society for the Promotion of Science (JSPS) JP21H05033MEXT | Japan Society for the Promotion of Science (JSPS) JP22H03214MEXT | Japan Society for the Promotion of Science (JSPS) JP23K05831MEXT | Japan Society for the Promotion of Science (JSPS) JP23K18328MEXT | Japan Society for the Promotion of Science (JSPS) JP23KJ1523MEXT | Japan Society for the Promotion of Science (JSPS) JP24K02033MEXT | Japan Society for the Promotion of Science (JSPS) JP24K09314MEXT | JST | Fusion Oriented REsearch for disruptive Science and Technology (FOREST) JPMJFR211FNICHD NIH HHS P01 HD087157NICHD NIH HHS R01 HD088412Takeda Science Foundation (TSF) NA
6 · The paper itself

Abstract

Sperm morphogenesis is a tightly regulated differentiation process, disruption of which leads to sperm malfunction and male infertility. Here, we show that

Indexed as

AcyltransferasesCell MembraneMembrane ProteinsMorphogenesisSperm HeadAnimalsInfertility, MaleLipoylationMaleMiceMice, KnockoutSpermatidsSpermatogenesisSpermatozoaTestisAcyltransferasesMembrane ProteinsS-acylationspermiationsterility

Identifiers

PMID40030029
PMCPMC11912386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.