Evidence map›Paper›PMID 40029675›Full record

Trial reportNoise & health

Sedative Effect of White Noise on Prefrontal Cortex Lobe: A Randomized Controlled Study Based on Functional Near-Infrared Spectroscopy.

Tiecheng Zhang, Yingfeng Tan, Jiayi Chen, Xiaofeng Jing, Rong Meng, Fan Xu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Noise & health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tiecheng ZhangDepartment of Evidence-Based Medicine and Social Medicine, School of Public Health, Chengdu Medical College, Sichuan, 610500, China.
Yingfeng TanDepartment of Pharmacy, Chengdu Medical College, Sichuan, 610500, China.
Jiayi ChenDepartment of Pharmacy, Chengdu Medical College, Sichuan, 610500, China.
Xiaofeng JingDepartment of Evidence-Based Medicine and Social Medicine, School of Public Health, Chengdu Medical College, Sichuan, 610500, China.
Rong MengDepartment of Evidence-Based Medicine and Social Medicine, School of Public Health, Chengdu Medical College, Sichuan, 610500, China.
Fan XuDepartment of Evidence-Based Medicine and Social Medicine, School of Public Health, Chengdu Medical College, Sichuan, 610500, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhite noise has attracted widespread attention due to its potential effects on psychological and physiological states, particularly in promoting relaxation. The prefrontal cortex, a critical region of the brain responsible for higher cognitive functions and emotional regulation, may influence an individual's mental and physical health through its responses to external stimuli. Although previous research has investigated the calming effects of white noise, systematic studies on its specific impact on prefrontal cortex activity are still lacking. This study aims to explore the calming effects of white noise on the prefrontal cortex to elucidate its associated physiological mechanisms.

methodsIn total, 103 healthy adult college students were recruited and randomly divided into four groups (fire, n = 24; wind, n = 27; rain, n = 27; and snow, n = 25), with each group exposed to the corresponding white noise for 3 min. Functional near-infrared spectroscopy (fNIRS) was used to evaluate excitability changes in the brain and changes in life signs and facial expressions were also measured.

resultsThe data of fNIRS were analyzed by paired sample t-test; in the wind group and the snow group, we found that the white noise can be effectively decreased the cortical excitability of related brain areas. The areas of reduced excitability were concentrated in the prefrontal cortex and pars triangularis of Broca's frontopolar area, while the concentration of oxyhemoglobin in these two area decreased from -0.159 to -0.107 µmol/L and from -0.139 to -0.096 µmol/L, respectively, both areas involved in relaxing and sedative modulation.

conclusionWhite noise can reduce the excitability of the prefrontal cortex and play a sedative effect. It may strengthen our understanding of how white noise is involved in neural modulation.

Indexed as

NoisePrefrontal CortexAdultFacial ExpressionFemaleHumansMaleOxyhemoglobinsSpectroscopy, Near-InfraredYoung AdultOxyhemoglobins

Identifiers

PMID40029675
PMCPMC11991127

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.