ArticleMethods in molecular biology (Clifton, N.J.)2025
Precision Cell-Cell Assembly Through Light-Mediated DNA Interactions.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Complex interactions between diverse cell populations influence processes ranging from cell division to programmed cell death. Replicating this complexity with reproducibility remains challenging. We introduce an innovative approach that combines DNA-mediated interactions with photolithography to achieve controlled cell-cell interactions. By coating cells with DNA sequences responsive to light, we enable meticulous spatial organization through light activation, facilitating rapid and programmable construction of intricate cell structures. This method not only addresses the challenges of orchestrating cell arrangements in vitro, particularly in three-dimensional settings but also offers a new avenue for the on-demand creation of complex cellular architectures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.