Evidence map›Paper›PMID 40029576›Full record

ArticleAIDS and behavior2025

Positive Psychological Factors Relate to Domain-Specific Cognition and Daily Functioning in Middle-Aged and Older Adults with HIV.

Lillian Ham, Maulika Kohli, Bin Tang, Igor Grant, David J Moore

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Update on neurological complications of HIV.Current opinion in HIV and AIDS · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lillian HamSan Diego Joint Doctoral Program in Clinical Psychology, San Diego State University, University of California, 220 Dickinson Street, San Diego, CA, 92103, USA.ORCID http://orcid.org/0000-0002-6163-9700
Maulika KohliVA Puget Sound Healthcare System, Seattle Division, Seattle, WA, USA.
Bin TangHIV Neurobehavioral Research Program, University of California San Diego, 220 Dickinson Street, Suite B (8231), San Diego, CA, 92103, USA.
Igor GrantHIV Neurobehavioral Research Program, University of California San Diego, 220 Dickinson Street, Suite B (8231), San Diego, CA, 92103, USA.
David J MooreHIV Neurobehavioral Research Program, University of California San Diego, 220 Dickinson Street, Suite B (8231), San Diego, CA, 92103, USA. djmoore@health.ucsd.edu.

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Multi-Dimensional Successful Aging Among HIV-Infected AdultsR01MH099987 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V., MOORE, DAVID J · 2013 to 2019
$3.8M
Developing a Risk Index for Functional Decline in Middle-Aged and Older Adults with HIVF31AG084417 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAM, LILLIAN · 2023 to 2024
$82k
Family history of dementia and APOE e4 status predict neurocognitive trajectories among persons with HIVF31AG074838 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KOHLI, MAULIKA · 2021 to 2022
$80k
California HIV/AIDS Research Program H22BD4432SNIA NIH HHS F31 AG074838NIA NIH HHS F31 AG084417NIH HHS P30 MH062512NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH099987
6 · The paper itself

Abstract

Understanding positive psychological factors (PPFs; internal strengths, socioemotional support) that promote optimal health outcomes among people with HIV (PWH) is increasingly important. 122 PWH and 98 people without HIV (PWoH) were included in multivariable regressions, testing interactions between HIV status and PPFs on 7 cognitive domains and 2 daily functioning outcomes, controlling for depressive symptoms. Overall, higher internal strengths were related to better learning and memory, whereas higher socioemotional support was related to better processing speed and psychomotor speed. PWH had a stronger positive relationship between PPFs and verbal fluency than PWoH. Overall, higher internal strengths were associated with fewer daily functioning impairments; however, only PWoH showed fewer functional declines with higher socioemotional support. PWH may require greater socioemotional support to accommodate an increased burden of comorbidities leading to functional difficulties. Among PWH, bolstering PPFs may improve cognition; however, internal strengths may particularly benefit daily functioning.

Indexed as

Activities of Daily LivingCognitionHIV InfectionsAgedDepressionFemaleHumansMaleMiddle AgedNeuropsychological TestsSocial SupportActivities of daily livingAgingNeurocognitive disordersPositive psychologyPsychological resilienceSocial support

Identifiers

PMID40029576
PMCPMC12031858

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.