Observational studyThe Psychiatric quarterly2025
International Trends in Antidepressant Consumption: a 10-year Comparative Analysis (2010-2020).
Observational study in The Psychiatric quarterly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Antidepressant use and the risk of atrial fibrillation and ventricular arrhythmia: A systematic review and meta-analysis.European journal of clinical pharmacology · 2026Pooled it
- Trends in age-sex-specific prevalence and incidence of antidepressant dispensation in the Nordic countries: a systematic review.British journal of clinical pharmacology · 2026Pooled it
- Selective serotonin reuptake inhibitors, erectile dysfunction, and the changing landscape of male sexual health.International journal of impotence research · 2026Review
- Antidepressant drug use in Europe: past consumption, prescribing patterns and forecast until 2030.International journal of clinical pharmacy · 2026Article
- Trazodone effectiveness in depression (TED): a comparative evaluation of effect sizes trazodone extended release and SSRIs in the treatment of major depressive disorder.Frontiers in pharmacology · 2026Article
- A Double Challenge for Fish: The Combined Stress of Warming and Pharmaceuticals in Aquatic Systems.Journal of xenobiotics · 2025Review
- Effective Degradation of Venlafaxine via Biochar Activated Persulfate: Kinetics, Transformation Products, and Toxicity Assessment.Molecules (Basel, Switzerland) · 2025Article
- Impact of COVID-19 on antidepressant prescription: a matched cohort study using the National insurance claims database in Japan.BMC psychiatry · 2025Article
- Trend analysis of antidepressant consumption in Italy from 2008 to 2022 in a public health perspective.Scientific reports · 2025Article
- Antidepressant use in the Canary Islands (Spain): a retrospective study of provincial, island and municipal trends and associated factors.Frontiers in pharmacology · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aims to analyze country-specific antidepressant consumption rates across 30 OECD countries, comparing them with the OECD average from 2010 to 2020. This analysis examines annual variations in consumption and identifies potential trends over time. Using a retrospective observational design, the study employs pooled secondary data from 30 OECD countries. A time trend analysis was conducted to assess overall and country-specific linear and quadratic trends, modeling the variation in Defined Daily Dose (DDD) per 1,000 inhabitants from 2010 to 2020. Findings reveal a significant increase in antidepressant consumption across most countries. The mean DDD value rose from 52.42 in 2010 to 69.5 in 2020. Three distinct trend patterns emerged: linear, concave, and convex. While 15 countries exhibited a significant linear increase, five showed a plateauing trend, and others experienced exponential growth with a convex trajectory. Denmark was the only country to show a decline in consumption, whereas Norway displayed no significant change over time. These results underscore a notable rise in antidepressant use across most OECD countries, alongside variations in consumption trajectories. By assessing and comparing national consumption rates, this study highlights the importance of international collaboration in addressing mental health challenges and optimizing healthcare accessibility and outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.