ReviewUrolithiasis2025
Environmental determinants in the development of kidney stone.
Review in Urolithiasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.Current urology reports · 2026Pooled it
- Stone composition and clinical characteristics of pediatric urolithiasis between Tibetan and non-Tibetan populations in Western China.Pediatric nephrology (Berlin, Germany) · 2026Article
- Impact of Calcium-Magnesium Ratio in Purified Water Remineralization on Calcium Oxalate Crystal Formation and Renal Injury.Nutrients · 2026Article
- Bioinformatic Analysis of Oxalate-Degrading Enzymes in Probiotics: A Systematic Genome-Scale and Structural Survey.Microorganisms · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The increase with years of kidney stone prevalence has become a serious public health problem worldwide. The geographical distribution pattern of kidney stone (known as "stone belt") clearly indicates the critical role of environmental exposure in its formation, which has long been an underestimated risk factor in studying the development of kidney stone. Based on our previous studies and bibliometric analysis, we discerned four environmental determinants and elaborated their impacts on human internal exposure related to kidney stone formation. The importance of climatic factor lies in that the relatively high temperature and low humidity environment may contribute greater prevalence of kidney stone, since it promotes elevating the concentration of relatively insoluble stone-forming salts. Geological factors including water quality, hydrogeology, and soil environment is involved in kidney stone formation via the food chain. Additionally, air pollution and heavy metal pollutants also act as potential risk factors by directly or indirectly affecting the normal renal function and urinary metabolism. This review thus provides insights into the specific mechanisms affecting metabolic changes in the human body which result in kidney stone formation under environmental exposure, and shed light on the pathogenesis of nephrolithiasis from an interdisciplinary perspective.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.