Evidence map›Paper›PMID 40029240›Full record

ArticleInfection and immunity2025

Structural basis of aggregative adherence fimbriae II interactions with sialic acid, mucin, and human intestinal cells.

Luke W Hagin, Inácio Mandomando, Fernando Ruiz-Perez, Nathan T Wright, Laura A Gonyar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luke W HaginDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia, USA.
Inácio MandomandoCentro de Investigação em Saúde de Manhiça, Maputo, Mozambique.
Fernando Ruiz-PerezDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia, USA.
Nathan T WrightDepartment of Chemistry and Biochemistry, James Madison University, Harrisonburg, Virginia, USA.
Laura A GonyarDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-5380-4254

Funding

Project 3 - Human colonoids as a model for the pathobiology of EHECP01AI125181 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FOULKE-ABEL, JENNIFER, KAPER, JAMES B · 2016 to 2025
$18.6M
Molecular Electron Microscopy Core Facility ImprovementsG20RR031199 · NCRR · UNIVERSITY OF VIRGINIA · PI SHUPNIK, MARGARET A · 2010 to 2010
$2.0M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) P01-AI125181National Science Foundation (NSF) MCB-2024182NCRR NIH HHS G20 RR031199NIAID NIH HHS P01 AI125181
6 · The paper itself

Abstract

Enteroaggregative

Indexed as

Adhesins, Escherichia coliBacterial AdhesionEscherichia coliFimbriae, BacterialMucinsN-Acetylneuraminic AcidBiofilmsFibronectinsHumansIntestinal MucosaProtein BindingAafA protein, E coliAdhesins, Escherichia coliFibronectinsMucinsN-Acetylneuraminic AcidbiofilmsEscherichia colifibronectinfimbriaeintestinal cellsmucinsialic acidstructural biology

Identifiers

PMID40029240
PMCPMC11977319

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.