Evidence map›Paper›PMID 40028672›Full record

ArticleClinical genetics2025

Limited Diagnostic Utility of PRDM10 Analysis in Birt-Hogg-Dubé Syndrome: Experience in 313 Consecutive Patients.

Agathe Hercent, Ibrahima Ba, Dimitri Tchernitchko

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Agathe HercentDepartment of Genetics, Bichat Hospital (APHP), Reference Laboratory for the Diagnosis of Birt Hogg Dube Syndrome, University of Paris Cité, Paris, France.
Ibrahima BaDepartment of Genetics, Bichat Hospital (APHP), Reference Laboratory for the Diagnosis of Birt Hogg Dube Syndrome, University of Paris Cité, Paris, France.
Dimitri TchernitchkoDepartment of Genetics, Bichat Hospital (APHP), Reference Laboratory for the Diagnosis of Birt Hogg Dube Syndrome, University of Paris Cité, Paris, France.ORCID 0000-0001-9820-0374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This short letter shows the limited diagnostic utility of PRDM10 screening in patients with a clinical suspicion of BHD syndrome. In a cohort of 313 patients with a suspicion of BHD syndrome and no FLCN mutations, none carry a pathogenic PRDM10 variation.

Indexed as

Birt-Hogg-Dube SyndromeHistone-Lysine N-MethyltransferaseProto-Oncogene ProteinsAdolescentAdultChildFemaleGenetic TestingHumansMaleMutationTumor Suppressor ProteinsHistone-Lysine N-MethyltransferaseProto-Oncogene ProteinsTumor Suppressor Proteins

Identifiers

PMID40028672
PMCPMC12136865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.