ReviewThe journal of liquid biopsy2023
"Plasma-first" approach for molecular genotyping in non-small cell lung cancer: A narrative review.
Review in The journal of liquid biopsy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
- Erratum issuedErratum.2024
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular genotyping is essential for management of patients newly diagnosed with advanced non-small cell lung cancer (NSCLC). Plasma circulating tumor DNA (ctDNA) testing has emerged as a complement to tumor tissue genotyping for advanced NSCLC, especially when tissue or time are limited. The optimal way to integrate ctDNA testing into the diagnostic algorithm for patients with newly diagnosed NSCLC remains unclear. A "plasma-first" approach, using ctDNA genotyping for patients with suspected or confirmed advanced NSCLC before tissue genotyping, may shorten time to treatment and yield a higher rate of detection of actionable genomic alterations. In this review, we discuss current evidence exploring the "plasma-first" approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.