Evidence map›Paper›PMID 40028278›Full record

ArticleiScience2025

Anti-osteoporotic effects and good biocompatibility of novel bioactive carbon quantum dots

Talante Juma, Guang-Hua Liang, Yang Jiao, Yuan-Yuan Ma, Bing-Xiao Yu, Yi-Min Guo, Xin Yang, Heng Liu, Zhi-Chao Meng, Rui Wang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  3. Carbon dots-based drug delivery for bone regeneration.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Talante JumaOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Guang-Hua LiangOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Yang JiaoOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Yuan-Yuan MaAnimal Experiment Center, Peking University First Hospital, Beijing 100034, China.
Bing-Xiao YuOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Yi-Min GuoChinaSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China.
Xin YangOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Heng LiuOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Zhi-Chao MengOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Rui WangOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Hao WuOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Li-Ping PanOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Hao WangOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Ya-Hong WangHarbin Chengcheng Institute for Material and Life, Harbin 150500, China.
Yong-Ping CaoOrthopaedic Department, Peking University First Hospital, Beijing 100034, China.
Tao ZhangChinaSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a prevalent condition among the elderly, and current treatments are limited by their side effects. This study aimed to develop a safe nanocarbon material with anti-osteoporotic properties. A promising candidate, carbon quantum dots (CQDs), was synthesized using a single-step liquid-phase pulse method and characterized by transmission electron microscopy (TEM). To evaluate the biocompatibility and anti-osteoporotic effects of CQDs, they were administered at a dose of 276 μg/mL or a placebo to an osteoporotic mouse model (

Indexed as

chemistryhealth sciencesPhysics

Identifiers

PMID40028278
PMCPMC11869970

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.