ArticleHeart views : the official journal of the Gulf Heart Association
Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block.
Article in Heart views : the official journal of the Gulf Heart Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Oxidative Stress, Environmental Pollutants, Aging, and Epigenetic Regulation: Mechanistic Insights and Biomarker Advances.Antioxidants (Basel, Switzerland) · 2026Review
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Authors and funding
13 authors.
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Abstract
Background: The majority of cases of complete heart block (CHB) still have an idiopathic etiology, despite recent advancements in CHB management. This previously unexplored aspect of CHB is examined in our work. In this study, we sought to evaluate the etiological characteristics of patients with CHB. Materials and Methods: Sixty patients with CHB, ranging in age from 30 to 80 years, who were admitted as inpatients to the emergency room made up the study population. Catalase (CAT) activity, serum malondialdehyde (MDA), serum glutathione (GSH), and serum superoxide dismutase (SOD) activity were used to measure oxidative stress. Serum total antioxidant capacity levels (TAOC) were used to calculate antioxidant activity. Tumor necrosis factor-alpha (TNF-alpha) and serum interleukin-5 (IL-5) levels were used to gauge the degree of inflammation. These numbers were contrasted with those of 30 healthy individuals who had never smoked or had diabetes mellitus. Individuals with drug-induced CHB and acute myocardial infarction were not accepted. Results: Out of 60 patients, the gender distribution was 37 men and 23 women, with a mean age of 62.48 ± 7.98 years. Serum MDA (ng/ml) has a mean value of 1451.26 ± 206.32 in patients and 1197.98 ± 234.71 in controls ( Conclusions: Serum MDA and inflammatory markers were markedly elevated during a CHB. This is particularly the case with IL-5, which was significantly increased in patients with CHB. According to our research, some inflammatory markers, such as IL-5 and oxidative markers like MDA, may actively contribute to the development of heart block.
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