Evidence map›Paper›PMID 40028238›Full record

ReviewBiomedical materials & devices (New York, N.Y.)2025

Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.

Rahimeh Rasouli, Crystal Sweeney, John P Frampton

Abstract readReview
In one paragraph

Review in Biomedical materials & devices (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Critical Systematic Review of 3D Bioprinting in Biomedicine.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rahimeh RasouliSchool of Biomedical Engineering, Dalhousie University, Halifax, Canada.
Crystal SweeneySchool of Biomedical Engineering, Dalhousie University, Halifax, Canada.
John P FramptonSchool of Biomedical Engineering, Dalhousie University, Halifax, Canada.ORCID 0000-0001-6245-1147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioink composition is a key consideration for the 3D-bioprinting of complex and stable structures used to model tissues and as tissue constructs for regenerative medicine. An emerging and industrially important area of research is the use of micro- and nanofillers to improve bioink performance without dramatically altering the physicochemical properties of the polymeric material that forms the bulk of the printed structure. The purpose of this review is to provide a comprehensive overview of emerging nanomaterial fillers designed to create heterogeneous and composite bioinks for 3D-bioprinting of complex functional tissues. We outline the criteria that must be considered when developing such a bioink and discuss applications where the fillers impart stimuli responsiveness, e.g., when exposed to magnetic fields, electrical fields, and light. We further highlight how the use of such fillers can enable non-destructive imaging to monitor scaffold placement and integrity following implantation.

Indexed as

3D-bioprintingBioinkHydrogelNanomaterialParticleRegenerative medicineStimuli responsivenessTissue engineering

Identifiers

PMID40028238
PMCPMC11868245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.