Evidence map›Paper›PMID 40028207›Full record

Observational studyPeerJ2025

Assessment of urinary oxidative stress biomarkers associated with fine particulate matter (PM2.5) exposure in Chiang Mai, Thailand.

Shamsa Sabir, Surat Hongsibsong, Hataichanok Chuljerm, Wason Parklak, Sakaewan Ounjaijean, Puriwat Fakfum, Sobia Kausar, Kanokwan Kulprachakarn

Abstract readObservational Study
In one paragraph

Observational study in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Seasonal PMToxics · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Impact of Seasonal PMToxics · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shamsa SabirSchool of Health Sciences Research, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Surat HongsibsongSchool of Health Sciences Research, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Hataichanok ChuljermSchool of Health Sciences Research, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Wason ParklakResearch Center for Non-infectious Diseases and Environmental Health, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Sakaewan OunjaijeanSchool of Health Sciences Research, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Puriwat FakfumResearch Center for Non-infectious Diseases and Environmental Health, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Sobia KausarSchool of Health Sciences Research, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Kanokwan KulprachakarnSchool of Health Sciences Research, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Exposure to fine particulate matter (PM2.5) is known to increase oxidative stress, impacting health adversely. This study examines the relationship between PM2.5 exposure and oxidative stress biomarkers in Chiang Mai, Thailand. Methods: A pilot prospective observational study was conducted in Samoeng District, Chiang Mai, including 25 healthy participants (age 25-60 years). Urine samples were collected during high (March-April 2023) and low (May-July 2023) PM2.5 seasons. PM2.5 concentrations were monitored daily from the Northern Thailand Air Quality Health Index (NTAQHI) system. Biomarkers analyzed included 1-hydroxypyrene (1-OHP) using high-performance liquid chromatography (HPLC), malondialdehyde (MDA) Results: Significant increases in urinary 1-OHP, MDA, and 8-epi-PGF2 Conclusions: This study highlights a significant association between elevated PM2.5 levels and increased oxidative stress biomarkers in Chiang Mai, Thailand. The findings suggest that exposure to higher concentrations of PM2.5 contributes to oxidative stress, potentially leading to adverse health outcomes.

Indexed as

Air PollutantsBiomarkersEnvironmental ExposureOxidative StressParticulate MatterAdultAir PollutionDinoprostEnvironmental MonitoringFemaleHumansMaleMalondialdehydeMiddle AgedPilot ProjectsProspective Studies1-hydroxypyrene8-epi-prostaglandin F2alphaAir PollutantsBiomarkersDinoprostMalondialdehydeParticulate MatterPyrenes1-Hydroxypyrene (1-OHP)8-epi-prostaglandin F2α(8-epi-PGF2α)BiomarkersChiang MaiMalondialdehyde (MDA)Oxidative stressPM2.5Thailand

Identifiers

PMID40028207
PMCPMC11871891

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.