Evidence map›Paper›PMID 40027858›Full record

ArticleJournal of oral biology and craniofacial research

Antibiofilm efficiency of silver and copper nanoparticle incorporated calcium hydroxide as an intracanal medicament: An

Murali H Rao, Krishnan Rajkumar, Gopal Pavithra, Ramya Ramadoss, Suryanarayanan Shankar, Krishnamachari Janani, Kumar Chandan Srivastava, Deepti Shrivastava, Dinesh Rokaya

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In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Murali H RaoDepartment of Conservative Dentistry and Endodontics D A Pandu Memorial RV Dental College, Bangalore, 560078, India.
Krishnan RajkumarDepartment of Oral Pathology ,SRM Dental College, Bharathi salai, Chennai Ramapuram Campus, SRMIST, Kattankulathur,Tamil Nadu, India.
Gopal PavithraDepartment of Dentistry and Endodontics D A Pandu Memorial RV Dental College, Bangalore, 560078, India.
Ramya RamadossDepartment of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences Chennai, 600077, India.
Suryanarayanan ShankarConservative Dentistry and Endodontics,D A Pandu Memorial RV Dental College, Bangalore, 560078, India.
Krishnamachari JananiDepartment of Conservative Dentistry and Endodontics, SRM Dental College, Bharathi salai, Chennai Ramapuram Campus, SRMIST, Kattankulathur, Tamil Nadu, India.
Kumar Chandan SrivastavaDepartment of Oral and Maxillofacial Surgery & Diagnostic Sciences, College of Dentistry, JOUF University, Sakaka, 72345, Saudi Arabia.
Deepti ShrivastavaDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, 72345, Saudi Arabia.
Dinesh RokayaDepartment of Prosthodontics, Faculty of Dentistry, Zarqa University, Zarqa, 13110, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Silver (Ag) and Copper (Cu) Nanoparticles (NP) are a potential substitute for disinfection during endodontic therapy because of their antibacterial action against an array of pathogens, including resistant strains. This study aimed to assess the antibiofilm efficiency of calcium hydroxide modified with Ag and Cu NP suspension against Methods: Dentine blocks were inoculated with Enterococcus faecalis for one week and 1 week-old biofilm of Results: CLSM images revealed a significant reduction in the thickness of biofilm in both Ag and Cu groups compared to calcium hydroxide alone. The CFU results showed that group 4 and group 3 showed significantly less CFU followed by group 2 and group 1 (p < 0.001). Conclusion: Adding Cu and Ag NP to calcium hydroxide intracanal medication significantly increases its antibacterial activity against

Indexed as

Calcium hydroxideCopper nanoparticleEndodontic treatmentSilver nanoparticle

Identifiers

PMID40027858
PMCPMC11870201

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.