Evidence map›Paper›PMID 40027853›Full record

ArticleJournal of oral biology and craniofacial research

"Effect of oral systemic administration of vitamin D on the rate of maxillary canine retraction: A randomized controlled trial".

Davender Kumar, Revathi Mn, Rekha Sharma, Ashuma Sachdeva, Nameksh Raj Bhupali, Ravinder Solanki

Abstract read
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Davender KumarDepartment of Orthodontics & Dentofacial Orthopaedics, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.
Revathi MnDepartment of Orthodontics & Dentofacial Orthopaedics, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.
Rekha SharmaDepartment of Orthodontics & Dentofacial Orthopaedics, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.
Ashuma SachdevaDepartment of Biochemistry, Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India.
Nameksh Raj BhupaliDepartment of Orthodontics & Dentofacial Orthopaedics, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.
Ravinder SolankiDepartment of Oral and Maxillofacial Surgery, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The trial was conducted to determine the effects of systemically delivered Vitamin D (1,25 dihydroxycholecalciferol) on the rate of maxillary canine retraction till the space closure and on the root resorption. Materials and methods: A two-arm parallel randomized controlled trial was conducted in patients with Angle's Class I bimaxillary protrusion requiring at least upper first premolars extraction and distal movement of canine for malocclusion correction. The enrolled patients were randomized and allocated to the experimental group (Oral Vitamin D = 0.25 μg given) and control group (Placebo given). The canine retraction was initiated using nickel-titanium (NiTi) closed coil springs delivering a force of 100 gm per side and Vitamin D levels were monitored at monthly intervals. The patients' casts were digitally scanned and examined for differences in the rate of canine retraction at initial (T0), 4 weeks (T1), 8 weeks (T2), 12 weeks (T3), 16 weeks (T4) and 20 weeks (T5) intervals were calculated. The volumetric root resorption was done on CBCT of the area of interest at T0 and after completion of retraction. Descriptive statistics and paired Results: 32 patients (18-24 years) were randomized in the experimental group (n = 16) and control group (n = 16) and no dropout was noted till the end of the study. The results showed a statistically significant increase in the rate of canine retraction in the experimental group as compared to the control group at different time intervals. The differences in the mean canine retraction between group 1 and group 2 at T1-T0, T2-T1, T3-T2, T4-T3, and T4-T0 were 0.28 ± 0.12, 0.29 ± 0.10, 0.31 ± 0.08, 0.37 ± 0.06 and 1.18 ± 0.10 mm respectively. The total mean canine retraction for group 1 was achieved at T4 time interval while it was achieved at T5 interval for group 2. The intergroup comparison of maxillary canine roots showed no statistically significant difference in volumetric root resorption. Conclusion: The active form of vitamin D can be an effective agent to accelerate orthodontic tooth movement (OTM).

Indexed as

Accelerated tooth movementCanine retractionRandomized controlled trialRoot resorptionVitamin D supplementation

Identifiers

PMID40027853
PMCPMC11869107

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.