Evidence map›Paper›PMID 40027818›Full record

ArticlebioRxiv : the preprint server for biology2025

An RNA Splicing System that Excises Transposons from Animal mRNAs.

Long-Wen Zhao, Christopher Nardone, Joao A Paulo, Stephen J Elledge, Scott Kennedy

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Degrons: defining the rules of protein degradation.Nature reviews. Molecular cell biology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Long-Wen ZhaoDepartment of Genetics, Harvard Medical School, Boston MA, 02115.
Christopher NardoneDepartment of Genetics, Harvard Medical School, Boston MA, 02115.
Joao A PauloDepartment of Cell Biology, Harvard Medical School, Boston MA, 02115.ORCID 0000-0002-4291-413X
Stephen J ElledgeDepartment of Genetics, Harvard Medical School, Boston MA, 02115.
Scott KennedyDepartment of Genetics, Harvard Medical School, Boston MA, 02115.

Funding

Ubiquitin Mediated Proteolysis and Cell Cycle ControlR01AG011085 · NIA · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JEFFREY W HARPER · 1993 to 2026
$10.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Non-Coding RNAs in Gene Regulation, Genome Defense, and Epigenetic InheritanceR35GM148206 · NIGMS · HARVARD MEDICAL SCHOOL · PI Scott G Kennedy · 2023 to 2026
$2.7M
NIA NIH HHS R01 AG011085NIGMS NIH HHS R35 GM148206NIH HHS P40 OD010440
6 · The paper itself

Abstract

All genomes harbor mobile genetic parasites called transposable elements (TEs). Here we describe a system, which we term SOS splicing, that protects

Identifiers

PMID40027818
PMCPMC11870413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.