Evidence map›Paper›PMID 40027738›Full record

ArticlebioRxiv : the preprint server for biology2025

Altered auditory feature discrimination in a rat model of Fragile X Syndrome.

D Walker Gauthier, Noelle James, Benjamin D Auerbach

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

D Walker GauthierDepartment of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois Urbana-Champaign, Urbana, Illinois, United States.
Noelle JamesDepartment of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois Urbana-Champaign, Urbana, Illinois, United States.ORCID 0000-0002-9936-5952
Benjamin D AuerbachDepartment of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois Urbana-Champaign, Urbana, Illinois, United States.ORCID 0000-0001-6253-2246

Funding

Identifying Convergent Circuit Disruptions Across Genetically-Distinct Models of AutismR01HD111753 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Benjamin D Auerbach · 2023 to 2026
$1.7M
Mechanisms of sound hypersensitivity in a rat model of autismK01DC018310 · NIDCD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI AUERBACH, BENJAMIN D · 2020 to 2024
$715k
NICHD NIH HHS R01 HD111753NIDCD NIH HHS K01 DC018310
6 · The paper itself

Abstract

Atypical sensory processing, particularly in the auditory domain, is one of the most common and quality-of-life affecting symptoms seen in autism spectrum disorders (ASD). Fragile X Syndrome (FXS) is the leading inherited cause of ASD and a majority of FXS individuals present with auditory processing alterations. While auditory hypersensitivity is a common phenotype observed in FXS and

Indexed as

auditory cortexautismfragile x syndromefrequency discriminationhyperexcitabilityinferior colliculussensory processingtuning

Identifiers

PMID40027738
PMCPMC11870463

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.