Evidence map›Paper›PMID 40027725›Full record

ArticlebioRxiv : the preprint server for biology2025

Extending scope and power of circular RNA research with circtools 2.0.

Shubhada R Kulkarni, Christoph Dieterich, Tobias Jakobi

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shubhada R KulkarniKlaus Tschira Institute for Integrative Computational Cardiology, Heidelberg, Germany.ORCID 0000-0003-2290-8004
Christoph DieterichKlaus Tschira Institute for Integrative Computational Cardiology, Heidelberg, Germany.ORCID 0000-0001-9468-6311
Tobias JakobiDepartment of Internal Medicine and the Translational Cardiovascular Research Center, University of Arizona, College of Medicine Phoenix, Phoenix, Arizona, United States.ORCID 0000-0002-3906-0401

Funding

Enabling comprehensive and user-friendly circular RNA analyses with circtools.cloudR01HG013124 · NHGRI · UNIVERSITY OF ARIZONA · PI Tobias Jakobi · 2024 to 2026
$2.0M
NHGRI NIH HHS R01 HG013124
6 · The paper itself

Abstract

Circular RNAs (circRNAs) play a pivotal role in gene regulation, acting as transcriptional modulators at various cellular levels and exhibit remarkable specificity across cell types and developmental stages. Detecting circRNAs from high-throughput RNA-seq data presents significant challenges, as it requires specialized tools to identify back-splice junctions (BSJ) in raw sequencing data. To address this need, we previously developed Availability: circtools 2.0 is available at github.com/jakobilab/circtools and licensed under GPLv3.0.

Indexed as

circRNAcircRNA analysiscircular RNAfull-length circRNAsingle-cell circRNAspatial circRNA

Identifiers

PMID40027725
PMCPMC11870457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.