Evidence map›Paper›PMID 40027707›Full record

ArticlebioRxiv : the preprint server for biology2025

Revisiting synthetic lethality of Gcn5-related N-acetyltransferase (GNAT) family mutations in

Katherine R Weber, Brianna Novillo, Julie A Maupin-Furlow

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Katherine R WeberDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.
Brianna NovilloDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.
Julie A Maupin-FurlowDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL, USA.ORCID 0000-0001-6105-0923

Funding

Ubiquitin-like Small Archaeal Protein Modification (SAMPylation)R01GM057498 · NIGMS · UNIVERSITY OF FLORIDA · PI MAUPIN-FURLOW, JULIE A · 2000 to 2024
$4.9M
NIGMS NIH HHS R01 GM057498
6 · The paper itself

Abstract

Lysine acetylation is a post-translational modification that occurs in all domains of life, highlighting its evolutionary significance. Previous genome comparison identified three Gcn5-related N-acetyltransferase (GNAT) family members as lysine acetyltransferase homologs (Pat1, Pat2, and Elp3) and two deacetylase homologs (Sir2 and HdaI) in the halophilic archaeon

Indexed as

archaeaHaloferax volcaniilysine acetyltransferasemutant generationpost-translational modification

Identifiers

PMID40027707
PMCPMC11870405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.