Evidence map›Paper›PMID 40027703›Full record

ArticlebioRxiv : the preprint server for biology2025

A novel peptidoglycan deacetylase modulates daughter cell separation in

Victor Hernandez-Rocamora, Alessandra M Martorana, Aitana Belloso, Daniel Ballesteros, Marta Zaccaria, Amilcar J Perez, Bogdan I Iorga, David Abia, Joe Gray, Eefjan Breukink and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Victor Hernandez-RocamoraCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-2517-5707
Alessandra M MartoranaDepartment of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", University of Milano, Milano, Italy.ORCID 0000-0003-3996-4141
Aitana BellosoCentro de Biología Molecular Severo Ochoa (CBM), CSIC - Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0009-0008-7265-2549
Daniel BallesterosCentro de Biología Molecular Severo Ochoa (CBM), CSIC - Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0009-0008-0799-2141
Marta ZaccariaDepartment of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", University of Milano, Milano, Italy.
Amilcar J PerezDepartment of Biophysics & Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-6729-7564
Bogdan I IorgaUniversité Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, Gif-sur-Yvette, France.ORCID 0000-0003-0392-1350
David AbiaCentro de Biología Molecular Severo Ochoa (CBM), CSIC - Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0003-0401-7590
Joe GrayCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Eefjan BreukinkMembrane Biochemistry and Biophysics, Bijvoet Centre for Biomolecular Research, Department of Chemistry, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-7311-0660
Jie XiaoDepartment of Biophysics & Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1433-5437
Manuel PazosCentro de Biología Molecular Severo Ochoa (CBM), CSIC - Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0002-8774-4453
Alessandra PolissiDepartment of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", University of Milano, Milano, Italy.
Waldemar VollmerCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-0408-8567

Funding

Spatial Organization and Regulation of Bacterial Cellular ProcessesR35GM136436 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Jie Xiao · 2020 to 2026
$4.8M
Elucidating the spatiotemporal regulation of septal peptidoglycan synthases in E.coliF32GM150262 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI PEREZ, AMILCAR JOSUE · 2023 to 2024
$151k
NIGMS NIH HHS F32 GM150262NIGMS NIH HHS R35 GM136436
6 · The paper itself

Abstract

Peptidoglycan hydrolases facilitate bacterial cell wall growth by creating space for insertion of new material and allowing physical separation of daughter cells. In

Identifiers

PMID40027703
PMCPMC11870482

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.