Evidence map›Paper›PMID 40027620›Full record

ArticlebioRxiv : the preprint server for biology2025

The interactome of the Bakers' yeast peroxiredoxin Tsa1 implicates it in the redox regulation of intermediary metabolism, glycolysis and zinc homeostasis.

Colin W MacDiarmid, Janet Taggart, Yirong Wang, Ajay Vashisht, Xin Qing, James A Wohlschlegel, David J Eide

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Colin W MacDiarmidDepartment of Pediatrics, University of Wisconsin-Madison, WI 53706.ORCID 0000-0001-8578-5756
Janet TaggartDepartment of Nutritional Sciences, University of Wisconsin-Madison, WI 53706.
Yirong WangDepartment of Nutritional Sciences, University of Wisconsin-Madison, WI 53706.
Ajay VashishtDepartment of Biological Chemistry, David Geffen School of Medicine at UCLA, CA 90095.
Xin QingDepartment of Nutritional Sciences, University of Wisconsin-Madison, WI 53706.ORCID 0000-0002-3579-706X
James A WohlschlegelDepartment of Biological Chemistry, David Geffen School of Medicine at UCLA, CA 90095.ORCID 0000-0003-3399-901X
David J EideDepartment of Nutritional Sciences, University of Wisconsin-Madison, WI 53706.ORCID 0000-0001-5386-2796

Funding

REGULATION OF CELLULAR ZINC HOMEOSTASISR01GM056285 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI EIDE, DAVID J · 1997 to 2022
$6.2M
Understanding Ubiquitin-dependent Regulation of Iron Metabolism using Mass SpectrometryR35GM153408 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI James Akira Wohlschlegel · 2024 to 2026
$1.2M
NIGMS NIH HHS R01 GM056285NIGMS NIH HHS R35 GM153408
6 · The paper itself

Abstract

Zinc (Zn) is an essential nutrient supporting a range of critical processes. In the yeast

Indexed as

interactomeperoxiredoxinredox regulationSaccharomyces cerevisiaeZap1Zinc

Identifiers

PMID40027620
PMCPMC11870615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.