Evidence map›Paper›PMID 40027571›Full record

ArticleWorld journal of hepatology2025

Survival of patients with hepatopulmonary syndrome related to cirrhotic and non-cirrhotic (schistosomiasis) portal hypertension.

Melissa M Rolim, Liana G Farsoun, Carlos F Luna, Brivaldo Markman-Filho, Paulo Querette, Edmundo P Lopes, Ana L Domingues

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PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melissa M RolimPostgraduate Program in Tropical Medicine, Center of Medical Sciences, Universidade Federal de Pernambuco, Recife 50670901, Pernambuco, Brazil. melissarolim.mr@gmail.com.
Liana G FarsounFaculdade de Medicina UniNassau, Grupo Ser Educacional, Recife 50100220, Pernambuco, Brazil.
Carlos F LunaStatistics and Geoprocessing Center, Institute Aggeu Magalhães, Oswaldo Cruz Foundation, Recife 50740465, Pernambuco, Brazil.
Brivaldo Markman-FilhoDepartment of Cardiology Division, Hospital das Clínicas/EBSERH-Universidade Federal de Pernambuco, Recife 50670901, Pernambuco, Brazil.
Paulo QuerettePostgraduate Program in Translational Health, Center of Medical Sciences, Universidade Federal de Pernambuco, Recife 50670901, Pernambuco, Brazil.
Edmundo P LopesPostgraduate Program in Tropical Medicine, Center of Medical Sciences, Universidade Federal de Pernambuco, Recife 50670901, Pernambuco, Brazil.
Ana L DominguesPostgraduate Program in Tropical Medicine, Center of Medical Sciences, Universidade Federal de Pernambuco, Recife 50670901, Pernambuco, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe hepatosplenic schistosomiasis (HSS) with portal hypertension can cause vascular complications such as hepatopulmonary syndrome (HPS). HPS increases the risk of mortality in patients with cirrhosis; however, there is no data on the mortality of patients with HSS and HPS.

aimTo perform a survival analysis of patients with HPS related to cirrhotic and non-cirrhotic (schistosomiasis) portal hypertension.

methodsFrom August 2023 to January 2024, medical records and the official mortality information service of 121 patients who participated in a cross-sectional study on HPS between 2010 and 2012 were analyzed. Survival curves were created using the Kaplan-Meier method, and comparisons were performed using the log-rank test. Cox regression models estimated the hazard ratios (HR).

resultsOverall, data of 113 patients were analyzed; most (55.8%) had HSS and concomitant cirrhosis (HSS/cirrhosis). Meanwhile, HPS was present in 39 (34.5%) patients. Death occurred in 65 patients [57.5%; 95% confidence interval (CI): 48%-67%. The average time to death was lower in those with HPS when compared to those without HPS (3.37 years

conclusionPatients with HSS and concomitant cirrhosis had a lower survival rate, but there was no difference in survival regardless of the presence of HPS.

Indexed as

Hepatopulmonary syndromeMortalityNon-cirrhotic portal hypertensionPortal hypertensionSchistosomiasisSurvival

Identifiers

PMID40027571
PMCPMC11866160

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