Evidence map›Paper›PMID 40027534›Full record

ArticleJournal of cutaneous and aesthetic surgery

A comparative study of the efficacy of potent topical corticosteroids per se versus combination of potent topical corticosteroids with fractional CO

Kishan Ninama, Rashmi Mahajan, Disha Baxi, Raveena Sanjay Patil, Yogesh Marfatia

Abstract read
In one paragraph

Article in Journal of cutaneous and aesthetic surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kishan NinamaDepartment of Dermatology, Venerology and Leprosy, Smt Bhikhiben K Shah Medical Institute and Research Center, Vadodara, Gujarat, India.
Rashmi MahajanDepartment of Dermatology, Venerology and Leprosy, Smt Bhikhiben K Shah Medical Institute and Research Center, Vadodara, Gujarat, India.
Disha BaxiDepartment of Dermatology, Venerology and Leprosy, Smt Bhikhiben K Shah Medical Institute and Research Center, Vadodara, Gujarat, India.
Raveena Sanjay PatilDepartment of Dermatology, Venerology and Leprosy, Smt Bhikhiben K Shah Medical Institute and Research Center, Vadodara, Gujarat, India.
Yogesh MarfatiaDepartment of Dermatology, Venerology and Leprosy, Smt Bhikhiben K Shah Medical Institute and Research Center, Vadodara, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The study aimed to compare the efficacy of two treatment modalities in vitiligo vulgaris that is - potent topical corticosteroid (betamethasone-dipropionate lotion 0.05%) with FrCO Material and Methods: Sixty cases with stable vitiligo (vitiligo vulgaris including focal vitiligo) >12 years of age with <27% body surface area were included in the study. The Institutional Ethics Committee approval was taken. After taking consent and clinical photographs, cases were randomly allocated into two groups of 30 patients each: Group A received FrCO Results: The mean vitiligo area scoring index (VASI) score at baseline for Group A was 1.17 ± 0.59, and after 3 months was 0.60 ± 0.56. For Group B, the mean VASI at baseline was 0.87 ± 0.35 and after 3 months was 0.63 ± 0.50. The p value of group B was 0.003 and for group A was 0.001. Even though the reduction in mean VASI was statistically significant in both groups, Group A showed a better response. Group A showed good to excellent response in 16.67% while Group B only cases in 3.3%. This suggests that the addition of FrCO Conclusion: The addition of FrCO

Indexed as

Fractional CO2Topical corticosteroidVitiligo

Identifiers

PMID40027534
PMCPMC11866677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.