Evidence map›Paper›PMID 40027505›Full record

SynthesisFrontiers in public health2025

The complex social, cultural and psychological drivers of the 'chemsex' experiences of men who have sex with men: a systematic review and conceptual thematic synthesis of qualitative studies.

Edward Mundy, Alexander Carter, Tom Nadarzynski, Christopher Whiteley, Richard O de Visser, Carrie D Llewellyn

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Chemsex and childhood trauma: evidence from a explorative matched case-control analysis.European archives of psychiatry and clinical neuroscience · 2026
    Article
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  3. Review
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  13. Article
  14. Syndemic Effects of Covid-19 Lockdown on Chemsex and HIV Among MSM in Malaysia: A Narrative Review.Journal of the International Association of Providers of AIDS Care
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edward MundySchool of Psychology, University of Kent, Canterbury, United Kingdom.
Alexander CarterDepartment of Primary Care and Public Health, Brighton & Sussex Medical School, University of Sussex, Falmer, United Kingdom.
Tom NadarzynskiSchool of Social Sciences, University of Westminster, London, United Kingdom.
Christopher WhiteleyCentral and North West London NHS Foundation Trust, London, United Kingdom.
Richard O de VisserDepartment of Primary Care and Public Health, Brighton & Sussex Medical School, University of Sussex, Falmer, United Kingdom.
Carrie D LlewellynDepartment of Primary Care and Public Health, Brighton & Sussex Medical School, University of Sussex, Falmer, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chemsex' is the sexualised use of drugs among men who have sex with men (MSM). Past systematic reviews have primarily focussed on quantitative research exploring the key characteristics and health consequences of chemsex. However, a large body of qualitative literature exists, drawing on different theoretical frameworks. Methods: A systematic review and thematic synthesis of the qualitative research on chemsex was conducted with the aim of exploring the chemsex experiences of MSM in the context of substance misuse and addictions, and to reviewing their underlying theoretical frameworks. Six databases were searched, and 43 papers were included in the review. Results: The thematic synthesis resulted in four key themes: 'characterising chemsex', 'the context around chemsex', 'the chemsex experience', and 'harms, saying safe, and stopping chemsex'. Only nine papers explicitly drew on theoretical frameworks, which were broadly divided into two categories: those which drew on psychological theories, and those that framed chemsex as a social and cultural phenomenon. Discussion: The results of the thematic synthesis add further understanding of the key characteristics of chemsex as well as some of the complex social and psychological drivers which may shape why people have chemsex. Finally, the review highlights the clinical implications and inherent complexities in providing clinical services for those reporting chemsex and the need for greater application of theory to advance our understanding of chemsex and continue to develop appropriate forms of therapeutic support. Systematic review registration: https://osf.io/j6k9r/.

Indexed as

Homosexuality, MaleIllicit DrugsSubstance-Related DisordersChemsexHumansMaleQualitative ResearchSexual BehaviorIllicit Drugschemsexmen who have sex with menpolydrug usequalitativesexualised drug usesubstance usesystematic review

Identifiers

PMID40027505
PMCPMC11869904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.