Evidence map›Paper›PMID 40027367›Full record

ReviewJournal of cardiovascular and thoracic research2024

Association between small dense low-density lipoprotein and carotid intima-media thickness.

Mohsen Khosravi, Farhad Sheikhnia, Mohammad Reza Pashaei, Maryam Karimi-Dehkordi, Shahin Alizadeh-Fanalou

Abstract readReview
In one paragraph

Review in Journal of cardiovascular and thoracic research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohsen KhosraviDepartment of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9815-7695
Farhad SheikhniaStudent Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
Mohammad Reza PashaeiPatient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Maryam Karimi-DehkordiDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
Shahin Alizadeh-FanalouDepartment of Clinical Biochemistry, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.ORCID https://orcid.org/0000-0003-0448-7074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) and atherosclerosis are major causes of mortality worldwide. Early and accurate diagnosis of vascular thickening by predictive markers can help reduce the death rate of these diseases. Low-density lipoprotein (LDL) particles, which are rich in cholesterol, are regarded as key biomarkers for CVD and atherosclerosis. Numerous studies have demonstrated that pattern B (small dense LDL, sdLDL) is more atherogenic than LDL and can serve as a superior quantitative marker for CVD than LDL. Furthermore, several studies have indicated that carotid intima-media thickness (cIMT) is a reliable marker for the early detection of CVD and atherosclerosis in various populations. This review examines the relationship between sdLDL concentration and cIMT. It is concluded that sdLDL concentration has a positive correlation with cIMT, and their combined use can facilitate a more precise assessment of the diseases, especially atherosclerosis.

Indexed as

AtherosclerosisCarotid intima-media thicknessCholesterolSmall dense low-density lipoprotein

Identifiers

PMID40027367
PMCPMC11866774

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.