Evidence map›Paper›PMID 40027347›Full record

ArticleRSC medicinal chemistry2025

Synthesis of fluorinated tubastatin A derivatives with bi-, tri-, and tetracyclic cap groups: molecular docking with HDAC6 and evaluation of

Huaxin Luo, Zheng Huang, Xiangdong Mo, Chunmei Long, Kaiyuan Wang, Rong Deng, Xiaofeng Zhu, Zhuo Zeng

Abstract read
In one paragraph

Article in RSC medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huaxin LuoSchool of Chemistry, South China Normal University Guangzhou 510006 People's Republic of China zhuoz@scnu.edu.cn.
Zheng HuangSchool of Chemistry, South China Normal University Guangzhou 510006 People's Republic of China zhuoz@scnu.edu.cn.
Xiangdong MoSchool of Chemistry, South China Normal University Guangzhou 510006 People's Republic of China zhuoz@scnu.edu.cn.
Chunmei LongSchool of Chemistry, South China Normal University Guangzhou 510006 People's Republic of China zhuoz@scnu.edu.cn.
Kaiyuan WangSchool of Chemistry, South China Normal University Guangzhou 510006 People's Republic of China zhuoz@scnu.edu.cn.
Rong DengState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center Guangzhou 510060 China dengrong@sysucc.org.cn zhuxfeng@mail.sysu.edu.cn.
Xiaofeng ZhuState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center Guangzhou 510060 China dengrong@sysucc.org.cn zhuxfeng@mail.sysu.edu.cn.
Zhuo ZengSchool of Chemistry, South China Normal University Guangzhou 510006 People's Republic of China zhuoz@scnu.edu.cn.ORCID https://orcid.org/0000-0003-4875-2909

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report the synthesis of 16 tubastatin A derivatives with fluorinated bi-, tri-, and tetracyclic cap groups. Most derivatives show strong

Identifiers

PMID40027347
PMCPMC11865918

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.