Evidence map›Paper›PMID 40027277›Full record

ArticleContemporary clinical trials communications2025

Kaat koort: Study protocol for a pragmatic randomized controlled trial of a multifactorial, multidisciplinary Aboriginal Health Practitioner-led Aboriginal dementia prevention intervention.

Carrington Cj Shepherd, Melissa A Dunham, Lina Gubhaju, Karen E Lamb, Digsu N Koye, Phoebe Fitzpatrick, Emily Banks, Kaarin J Anstey, Melinda Carrington, Daniel McAullay and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Advancing brain health equity with Indigenous peoples: A critical imperative.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Carrington Cj ShepherdCurtin Medical School, Curtin University, Kent Street, 6102, Bentley, Australia.
Melissa A DunhamCurtin Medical School, Curtin University, Kent Street, 6102, Bentley, Australia.
Lina GubhajuCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207-221 Bouverie Street, 3010, Melbourne, Australia.
Karen E LambCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207-221 Bouverie Street, 3010, Melbourne, Australia.
Digsu N KoyeCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207-221 Bouverie Street, 3010, Melbourne, Australia.
Phoebe FitzpatrickCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207-221 Bouverie Street, 3010, Melbourne, Australia.
Emily BanksNational Centre for Epidemiology and Population Health, Australian National University, 62 Mills Rd, 2601, Acton, Australia.
Kaarin J AnsteySchool of Psychology, University of New South Wales, Mathews Building, 2052, Kensington, Australia.
Melinda CarringtonBaker Heart and Diabetes Institute, 75 Commercial Rd, 3004, Melbourne, Australia.
Daniel McAullayKurongkurl Katitjin, Edith Cowan University, 2 Bradford St, Mount Lawley, 6050, Australia.
Ofra Kalter-LeiboviciGertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, 52126, Ramat Gan, Israel.
Grace JoshyNational Centre for Epidemiology and Population Health, Australian National University, 62 Mills Rd, 2601, Acton, Australia.
Lesley NelsonSouth West Aboriginal Medical Service, 51/55 Forrest Avenue, 6230, Bunbury, Australia.
Jason AgostinoAcademic Unit of General Practice, Australian National University, 0200, Canberra, Australia.
Ellie PaigeNational Centre for Epidemiology and Population Health, Australian National University, 62 Mills Rd, 2601, Acton, Australia.
Kathleen Abu-SaadGertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, 52126, Ramat Gan, Israel.
Elise AlexanderCentre for Aboriginal Medical and Dental Health (CAMDH), Medical School, University of Western Australia, 35 Stirling Hwy, 6009, Crawley, Australia.
Rona MacNivenSchool of Population Health, Faculty of Medicine & Health, UNSW Sydney, 2052, Kensington, Australia.
Kelsey GriffenSchool of Population Health, Faculty of Medicine & Health, UNSW Sydney, 2052, Kensington, Australia.
Fiona CollinsSouth West Aboriginal Medical Service, 51/55 Forrest Avenue, 6230, Bunbury, Australia.
Salena Linforth-MilhamSouth West Aboriginal Medical Service, 51/55 Forrest Avenue, 6230, Bunbury, Australia.
Dolores GilbertDerbarl Yerrigan Health Service, 156 Wittenoom Street, East Perth, 6004, Australia.
Cindy PriorThe Kids Research Institute Australia, 15 Hospital Ave, Nedlands, 6009, Australia.
Sadia RindDerbarl Yerrigan Health Service, 156 Wittenoom Street, East Perth, 6004, Australia.
Richelle DouglasDerbarl Yerrigan Health Service, 156 Wittenoom Street, East Perth, 6004, Australia.
Sandra EadesCurtin Medical School, Curtin University, Kent Street, 6102, Bentley, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited available data indicate that dementia prevalence rates among Aboriginal and Torres Strait Islander (hereafter Aboriginal) peoples are 3-5 times higher than the overall Australian population. Effective, pragmatic and scalable interventions are urgently required to address this disproportionate burden of dementia in Aboriginal populations. Methods: Kaat Koort is a pragmatic two-arm parallel-group randomized controlled trial which will recruit a sample of 354 participants from two Aboriginal community-controlled health services in the south-west of Western Australia. Eligible participants are aged 35-60 years with risk factors for cardiovascular disease. Participants will be randomized in a 1:1 ratio to receive either a 12-month multifactorial lifestyle intervention (guided by Aboriginal Health Practitioners) that involves cardiovascular risk management, a lifestyle program targeting diet and physical activity, and support for smoking cessation and depression, or usual care (control). The primary endpoints are change in (i) systolic, and (ii) diastolic blood pressure. Secondary endpoints are changes in other cardiovascular risk factors (elevated blood pressure, HDL cholesterol, HbA1c, waist circumference, and absolute cardiovascular risk score), cognitive functioning, and adherence to Australian dietary and physical activity guidelines. Outcomes will be collected at baseline, and 6- and 12-months post-baseline. Discussion: This trial aims to determine the efficacy of a multifactorial lifestyle intervention in reducing blood pressure among Aboriginal people aged 35-60 years at risk of dementia. Trial registration number: ACTRN12621001022853; Australian New Zealand Clinical Trial Registry identifier.

Indexed as

Aboriginal/Torres Strait Islander peoplesBlood pressureCardiovascular diseaseCognitive declineDementiaIndigenousRandomized controlled trial

Identifiers

PMID40027277
PMCPMC11872118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.