ArticleFrontiers in neurology2025
Clinical implications of real-time optic nerve sheath diameter assessment via critical care ultrasound in intracranial hypertension.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07786324 (Comparison of 3% Hypertonic Saline Versus 20% Mannitol in Reduction of Increased Intracranial Pressure in Patients With Traumatic Brain Injury Using Optic Nerve Sheath Diameter Measurements''), which is not on this map. Cited by 4 papers.
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Comparison of 3% Hypertonic Saline Versus 20% Mannitol in Reduction of Increased Intracranial Pressure in Patients With Traumatic Brain Injury Using Optic Nerve Sheath Diameter Measurements''
Who cites it
4 citing papers in PubMed.
- Commentary on: Ultrasound Measurement of Dynamic Changes in Optic Nerve Sheath Diameter During Liposuction Surgery: A Prospective Clinical Trial.Aesthetic plastic surgery · 2026Article
- 3D Freehand Ultrasound Imaging of Optic Nerve Sheath.Investigative radiology · 2026Article
- Evaluation of Intracranial Pressure in Patients with Severe Brain Injury Using Contrast-Enhanced Ultrasound: A Pilot Study with Preliminary Findings.Neurocritical care · 2026Observational
- Brain-based symptoms reported in young adults evaluated for cervical spine etiology: a retrospective, cross-sectional clinical study with preliminary data on over 200 patients.Frontiers in neurologyArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aims to assess the clinical value of dynamic monitoring of optic nerve sheath diameter using critical care ultrasound in the management of patients with intracranial hypertension. Methods: A total of 130 patients with craniocerebral injuries, treated at the Department of Critical Care Medicine of the Affiliated Hospital of Hebei University from January 2021 to November 2022, were selected and randomly assigned to either the control group (65 patients) or the observation group (65 patients). Patients in both groups were monitored based on clinical symptoms, cranial CT findings, and optic nerve sheath diameter (ONSD). The control group received standard osmotic therapy to manage intracranial pressure (ICP), while the observation group was guided accordingly. Comparative analyses were conducted on Acute Physiology and Chronic Health Evaluation II (APACHE II) scores, Glasgow Coma Scale (GCS) scores, duration of ICU stay, and mechanical ventilation time between the two groups. Results: On the 28th day, the APACHE II scores of patients with craniocerebral injuries in both groups were significantly lower compared to admission scores, while GCS scores were higher ( Conclusion: Dynamic monitoring of ONSD using bedside critical care ultrasound has proven effective in guiding osmotic therapy for patients with intracranial hypertension. This approach significantly reduces ICP, offers a reliable basis to opt for subsequent treatments, and effectively lowers the rate of disability while improving patient prognosis.
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