Evidence map›Paper›PMID 40027144›Full record

ArticleThe journal of liquid biopsy2024

Exosomes-based liquid biopsy: An effective approach for drugs and therapeutics resistance screening in cancer.

Sidhanti Nyahatkar, Ketki Kalele

Abstract read
In one paragraph

Article in The journal of liquid biopsy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sidhanti NyahatkarVYWS Dental College & Hospital, WQMV+7X6, Tapovan-Wadali Road, Camp Rd, SRPF Colony, Amravati, Maharashtra, 444602, India.
Ketki KaleleNeuron Institute of Applied Research, Rajapeth-Irwin Square Flyover, Amrawati Tahsil, Amravati, Maharashtra, 444601, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer drugs and therapeutics resistance are a complicated domain of cancer treatment. Extracellular vesicles (EVs) based cancer investigation reveals several complicated concepts about cancer. EVs are associated with cellular communication. Its bioactive molecular transportation reprograms cellular activity. Exosomes an exciting EVs subpopulation work as masterminds in cancer development and progression. Studies over the past decade have elucidated that exosomes play a vital role in intercellular communication within the tumor microenvironment (TME), influencing multiple events such as hypoxia-induced epithelial-mesenchymal transition (EMT), cancer stemness, angiogenesis, and metastasis. Tumor-derived exosomes (TEXs) associated with drugs and therapeutics resistance development. This article focuses on understanding exosome biology and its implications in cancer drug and therapeutics resistance, exosome-based liquid biopsy application in drug and therapeutic resistance detection, limitations, and future orientation in this domain.

Indexed as

Drug resistanceExosomesmicroRNATherapeutic resistance

Identifiers

PMID40027144
PMCPMC11863703

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.