Evidence map›Paper›PMID 40027082›Full record

ArticleFrontiers in physiology2025

On the nose: nasal neurostimulation as a technology countermeasure for sinonasal congestion in astronauts.

Timon Ax, Philipp H Zimmermann, Tomas L Bothe, Karen Barchetti, Cintia S de Paiva, Francesc March de Ribot, Slade O Jensen, Thomas J Millar

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Timon AxSchool of Medicine, Western Sydney University, Sydney, NSW, Australia.
Philipp H ZimmermannDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty, University of Cologne, Cologne, Germany.
Tomas L BotheInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Karen BarchettiUniversité Paris Cité, Faculté de Pharmacie, MTCI ED 563, Paris, France.
Cintia S de PaivaOcular Surface Center, Department of Ophthalmology, Baylor College of Medicine, Cullen Eye Institute, Houston, TX, United States.
Francesc March de RibotDepartment of Ophthalmology, Otago University, Dunedin, New Zealand.
Slade O JensenSchool of Medicine, Western Sydney University, Sydney, NSW, Australia.
Thomas J MillarBeyond 700 Pty Ltd, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human spaceflight subjects the body to numerous and unique challenges. Astronauts frequently report a sense of sinonasal congestion upon entering microgravity for which the exact pathomechanisms are unknown. However, cephalad fluid shift seems to be its primary cause, with CO

Indexed as

countermeasurehuman spaceflightmicrogravitynasal congestionneurostimulationsinusitissinus pain

Identifiers

PMID40027082
PMCPMC11868271

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.