Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Disease: A Review of the Existing Literature.

Chmsalddin Alkhas, George G Kidess, Matthew T Brennan, Jawad Basit, Farah Yasmin, Wael Jaroudi, M Chadi Alraies

Abstract readReview

In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Two-year outcomes of transcatheter aortic valve replacement with the vitaflow libertyTM system in high-surgical-risk patients with severe aortic stenosis.Journal of cardiothoracic surgery · 2026
Trial

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chmsalddin AlkhasDepartment of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, USA.

George G KidessDepartment of Medicine, Wayne State University School of Medicine, Detroit, USA.

Matthew T BrennanDepartment of Medicine, Wayne State University School of Medicine, Detroit, USA.

Jawad BasitDepartment of Surgery, Holy Family Hospital, Rawalpindi, PAK.

Farah YasminDepartment of Internal Medicine, Yale School of Medicine, New Haven, USA.

Wael JaroudiDepartment of Cardiovascular Medicine, Clemenceau Medical Center, Beirut, LBN.

M Chadi AlraiesDepartment of Cardiology, Wayne State University Detroit Medical Center, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure used to replace a damaged aortic valve with a prosthetic valve. TAVR has exceeded surgical aortic valve replacement (SAVR) due to shorter procedures and recovery times. Though initially approved for patients with aortic stenosis at a high surgical risk, TAVR's indications have now broadened to include high, intermediate, and low-risk patients. This review focuses on the evolving role of TAVR in patients with bicuspid aortic valves (BAV). We examine the anatomical and hemodynamic differences between tricuspid aortic valve and BAV, highlighting the unique challenges TAVR faces in BAV patients.

Indexed as

bicuspid aortic valve diseasetranscatheter aortic replacementtranscatheter aortic valve implanttranscatheter aortic valve implantation (tavi)vulvular heart disease

Identifiers

PMID40027070

DOI10.7759/cureus.78192

PMCPMC11870031

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.