Evidence map›Paper›PMID 40027050›Full record

ArticleCureus2025

Tricuspid Endocarditis Leading to a Stroke: A Case Report of Paradoxical Embolism in a Young Intravenous Drug User.

Khaleel Quasem, Michelle Carrasquel, Varun George, Lee Elisevich, Haley Maser

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khaleel QuasemInternal Medicine, McLaren Greater Lansing, Lansing, USA.
Michelle CarrasquelInternal Medicine, Mclaren Greater Lansing, Lansing, USA.
Varun GeorgeCardiology, McLaren Greater Lansing, Lansing, USA.
Lee ElisevichInternal Medicine, McLaren Greater Lansing, Lansing, USA.
Haley MaserInternal Medicine, McLaren Greater Lansing, Lansing, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infective endocarditis (IE) involving the tricuspid valve is commonly associated with intravenous drug use, with right-sided IE typically leading to septic pulmonary emboli; however, systemic embolization via paradoxical embolism is a rare and severe complication. We present a case of a 33-year-old female with a history of intravenous drug use who was admitted with generalized pain after leaving another facility against medical advice following treatment for pneumonia and tricuspid valve endocarditis, including vegetation debulking. On readmission, she exhibited signs of infection, and imaging revealed bilateral septic pulmonary emboli with cavitary lesions, while echocardiography showed severe tricuspid regurgitation with large mobile vegetation and an aneurysmal interatrial septum, suggesting a probable patent foramen ovale. Despite management with intravenous antibiotics for

Indexed as

antiplatelet therapycerebral infarctioninfective endocarditisintracardiac shuntintravenous drug userparadoxical embolismpatent foramen ovaleseptic pulmonary embolitricuspid valve endocarditis

Identifiers

PMID40027050
PMCPMC11872280

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.