Evidence map›Paper›PMID 40027035›Full record

ArticleCureus2025

A Rare Case of a Solitary Central Nervous System Tuberculoma Mimicking an Intracranial Tumor.

Aikaterini Gakidi, Eleni Faniadou, Despoina Ioannidou, Afroditi Boutou

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aikaterini GakidiDepartment of Respiratory Medicine, Hippokration Hospital, Thessaloniki, GRC.
Eleni FaniadouDepartment of Respiratory Medicine, Hippokration Hospital, Thessaloniki, GRC.
Despoina IoannidouDepartment of Respiratory Medicine, Hippokration Hospital, Thessaloniki, GRC.
Afroditi BoutouDepartment of Respiratory Medicine, Hippokration Hospital, Thessaloniki, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) can sometimes involve the central nervous system (CNS), especially among immunocompromised patients, but it is an infrequent manifestation. Among immunocompetent individuals, CNS TB has only scarcely been described in the literature; when it is manifested as a solitary lesion (tuberculoma), it can mimic other CNS tumors, appearing with clinical manifestations of increased intracranial pressure, such as headaches and vomiting. In this manuscript, we describe a case of a CNS tuberculoma, which presented as a cerebellum tumor with signs of increased intracranial pressure in an immunocompetent pregnant woman. Caesarian section and craniotomy with tumor excision were performed. Mycobacterium TB sensitive to rifampicin was identified in the tissue block, anti-TB treatment was initiated, and the patient's condition improved. The temporary immunosuppressive state of pregnancy may lead to the reactivation of TB infection, along with clinical manifestations from extrapulmonary sites, such as the CNS. Awareness of CNS tuberculomas and their clinical manifestations should be raised, as early recognition and treatment are important for a successful outcome.

Indexed as

central nervous system tuberculosisimmunocompetent patientintracranial pressurepregnancysolitary brain lesion

Identifiers

PMID40027035
PMCPMC11870648

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.