ArticleCureus2025
Impact of Vitamin D Levels on Clinical Outcomes in SARS-CoV-2 Infections.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Associations Between Serum 25(OH)D Concentrations and Clinical Characteristics in Pediatric Patients.Reports (MDPI) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimSince its emergence in 2019, SARS-CoV-2 has caused the global COVID-19 pandemic, presenting significant challenges for healthcare systems worldwide. Extensive research has focused on diagnostics, treatments, and vaccine development to combat the virus. Given the need for effective strategies to reduce infection rates, disease progression, and severity, this study aimed to investigate the potential role of vitamin D (25OHD) in mitigating the severity of COVID-19.
methodsA cross-sectional study was conducted to evaluate the relationship between serum vitamin D levels and the severity of COVID-19 symptoms. Vitamin D levels were measured using the Roche Diagnostics Vitamin D assay in 100 SARS-CoV-2-infected patients confirmed by real-time polymerase chain reaction (PCR). Patients were categorized as symptomatic or asymptomatic, and the correlation between vitamin D levels and symptom severity was analyzed.
resultsThe findings demonstrated that a significant proportion of symptomatic patients had vitamin D levels below 20 ng/mL. In contrast, approximately 25% of asymptomatic patients had vitamin D levels exceeding 30 ng/mL. Statistical analysis confirmed a significant association between low vitamin D levels and increased symptom severity (p=0.007).
conclusionThis study suggests that vitamin D deficiency may contribute to the severity of COVID-19 symptoms. Vitamin D supplementation could potentially reduce the risk of severe disease. However, to confirm these findings and support these recommendations, further research, including randomized controlled trials and large-scale population studies, is necessary.
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