ArticleCureus2025
Varus-Valgus Constrained Prostheses in Revision Total Knee Arthroplasty: A Retrospective Study of Mid- to Long-Term Outcomes.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Total knee arthroplasty (TKA) is a well-established treatment for end-stage knee arthritis, providing substantial pain relief and functional improvement. However, the increasing need for revision TKA (RTKA) due to factors such as polyethylene wear, aseptic loosening, periprosthetic infection, and instability presents significant challenges. This study aimed to assess the mid- to long-term clinical and radiographic outcomes, implant survival rates, and complications associated with RTKA using a varus-valgus constrained (VVC) prosthesis. Methods This retrospective observational study analyzed patients who underwent RTKA with either VVC or condylar constrained knee prostheses at Sunshine Hospitals in Hyderabad, India, between January 1, 2010 and January 1, 2020, with a minimum follow-up of four years. Data were obtained from the joint registry. The inclusion criteria encompassed patients who underwent single-stage or two-stage RTKA for any indication, including periprosthetic joint infection (PJI), instability, or aseptic loosening. Functional outcomes were assessed using the Knee Society Score (KSS) and Oxford Knee Score (OKS), while radiolucent lines were evaluated with the updated Knee Society Roentgenographic Score. Implant survival rates were analyzed using Kaplan-Meier survival analysis. Results A total of 139 patients met the eligibility criteria for the final analysis, with a mean follow-up of 6.3 ± 2.4 years. The cohort had a mean age of 64.8 ± 7.8 years, comprising 90 females (64.7%), and a mean BMI of 29.3 ± 5.4. The primary indications for RTKA were PJI (70 cases, 50.4%) and aseptic loosening (47 cases, 33.8%). Significant postoperative improvements were observed in range of motion (from 73.2 degrees preoperatively to 104.3 degrees postoperatively), OKS (from 14.3 to 29.2), and KSS (from 48.2 to 74.9), all of which were highly significant (p < 0.001). Radiolucent lines were detected in 13 femoral components (9.35%) and 18 tibial components (12.95%), with one case progressing to aseptic loosening. Complications included superficial surgical site infections (two cases, 1.4%) and persistent prosthetic joint infections (three cases, 2.2%). Kaplan-Meier survival analysis demonstrated a 98.3% survival rate at 60 months, with reoperation for any cause as the endpoint. Conclusions The use of VVC prostheses in RTKA yields favorable long-term outcomes, demonstrating high survival rates and significant functional improvements. While managing bone defects and preventing postoperative infections remain challenges, meticulous surgical techniques and comprehensive postoperative care play a crucial role in achieving reliable results. These factors contribute to improved patient outcomes and enhanced prosthesis longevity in complex RTKA cases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.