ArticleCureus2025
Acute Functional Gastric Outlet Obstruction Associated With Low-Dose Tirzepatide.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Incretin-Based Drugs for Obesity: Common and Drug-Specific Reporting Patterns of Adverse Drug Reactions-A Comparative Disproportionality Analysis Using EudraVigilance Reports Integrating SmPC Data.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Not Just Skin Deep: A Hidden Complication of Tirzepatide Therapy.Obesity surgery · 2025Article
- A retrospective observational study on case reports of adverse drug reactions (ADRs) to tirzepatide.Frontiers in pharmacology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity has become a significant global challenge, highlighting the need for effective weight loss strategies. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as a promising solution, with tirzepatide gaining significant popularity for its efficacy in promoting weight loss. This case report highlights a 57-year-old male patient with type 2 diabetes on a low dose of tirzepatide who initially presented with severe abdominal pain and vomiting, with symptoms resembling those of acute functional gastric outlet obstruction. Despite initial suspicion of an anatomical obstruction, no abnormalities were found on esophagogastroduodenoscopy. The symptoms resolved following the discontinuation of tirzepatide, suggesting a causative link. This case underscores the importance of physician awareness and patient education regarding potential severe gastrointestinal side effects associated with tirzepatide, even at low doses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.