Evidence map›Paper›PMID 40026929›Full record

ArticleCureus2025

Extremely High Preoperative Parathyroid Hormone Associated With Severe Postoperative Hungry Bone Syndrome-Induced Delirium in a Case of Parathyroid Carcinoma in Vietnam: A Case Report.

Ly Na Dau, Ngoc Diep B Nguyen, Minh D Do, Hoang V Lam

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ly Na DauEndocrinology and Metabolism, Cho Ray Hospital, Ho Chi Minh, VNM.
Ngoc Diep B NguyenPathology, Cho Ray Hospital, Ho Chi Minh, VNM.
Minh D DoEndocrinology and Metabolism, Cho Ray Hospital, Ho Chi Minh, VNM.
Hoang V LamEndocrinology and Diabetes, Tam Anh Hospital, Ho Chi Minh, VNM.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid carcinoma (PC) is one of the rarest cancers, accounting for less than 1% of all cases of primary hyperparathyroidism worldwide. The preoperative level of parathyroid hormone (PTH) has been taken as an essential index in diagnosing and prognosting PC. The conventional range of preoperative PTH was three to 10 times higher than the upper limit. Recently published studies have shown a significantly extensive range of preoperative levels of PTH in different countries, which might change our opinion on probable preoperative PTH levels in PC and its related postoperative complications. We present a case of a 47-year-old Vietnamese male patient suffering from PC with preoperative PTH up to 60 times higher than the upper limit. After the surgery, the patient developed hungry bone syndrome (HBS), manifesting through severe hypocalcemia at 0.04 mmol/l of ionized calcium, which altered his mental status for one week and required a hefty dose of calcium to normalize the patient's plasma calcium levels. There seems to be no upper limit for PTH levels in PC. A significantly high level of preoperative PTH is an essential warning sign of severe HSB developing postoperatively.

Indexed as

case reportdeliriumhungry bone syndromehypocalcemiaparathyroid carcinoma

Identifiers

PMID40026929
PMCPMC11871375

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.