Evidence map›Paper›PMID 40026910›Full record

ArticlePhysics and imaging in radiation oncology2025

Effect of end expiration breath hold on target volumes and organ at risk doses for oesophageal cancer radiotherapy.

Christopher Mayhew, Jeyaanth Venkatasai, Marina Khan, Victoria Butterworth, Kasia Owczarczyk, Georgios Ntentas

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher MayhewDepartment of Medical Physics and Clinical Engineering Guy's and St Thomas' NHS Foundation Trust London UK.
Jeyaanth VenkatasaiDepartment of Oncology Guy's Cancer Centre Guy's and St Thomas' NHS Foundation Trust London UK.
Marina KhanDepartment of Radiotherapy Guy's Cancer Centre Guy's and St Thomas' NHS Foundation Trust London UK.
Victoria ButterworthDepartment of Medical Physics and Clinical Engineering Guy's and St Thomas' NHS Foundation Trust London UK.
Kasia OwczarczykDepartment of Oncology Guy's Cancer Centre Guy's and St Thomas' NHS Foundation Trust London UK.
Georgios NtentasDepartment of Medical Physics and Clinical Engineering Guy's and St Thomas' NHS Foundation Trust London UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: The end expiration breath hold (EEBH) technique has the potential to reduce tumour motion during radiotherapy treatment of lower oesophageal cancer, and therefore, motion artefacts, target volumes and dose to surrounding organs at risk (OAR). EEBH is an emerging technique and clinical data on its use in oesophageal cancer is scarce. Methods and Materials: A comparison of 20 lower oesophageal cancer patients was performed for radiotherapy treatment plans in both EEBH and free breathing (FB). EEBH and FB plans were evaluated and compared in terms of motion artefacts, target volumes and dose-volume metrics. Results: EEBH was effective in reducing the observed motion artefacts seen in planning CTs compared to FB. EEBH also significantly reduced the average PTV size between EEBH and FB (ΔV = -48 ± 55 cm Conclusion: Use of EEBH for oesophageal cancer radiotherapy reduced motion artefacts and increased confidence in contouring volumes. Additionally, planning target volumes and doses to key OARs were reduced with EEBH compared to FB plans.

Indexed as

EEBHEnd expiration breath holdOesophageal cancer

Identifiers

PMID40026910
PMCPMC11871499

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.