Evidence map›Paper›PMID 40026908›Full record

ArticlePhysics and imaging in radiation oncology2025

First dosimetric evaluation of clinical raster-scanned proton, helium and carbon ion treatment plan delivery during simultaneous real-time magnetic resonance imaging.

Sebastian Klüter, Karolin Milewski, Wibke Johnen, Stephan Brons, Jakob Naumann, Stefan Dorsch, Cedric Beyer, Katharina Paul, Kilian A Dietrich, Tanja Platt and 2 more

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In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sebastian KlüterDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Karolin MilewskiDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Wibke JohnenHeidelberg Institute of Radiation Oncology (HIRO), National Center for Radiation Oncology (NCRO), Heidelberg, Baden-Württemberg, Germany.
Stephan BronsHeidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Baden-Württemberg, Germany.
Jakob NaumannHeidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Baden-Württemberg, Germany.
Stefan DorschDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Cedric BeyerDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Katharina PaulDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Kilian A DietrichDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Tanja PlattMedical Physics in Radiology, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.
Jürgen DebusDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Julia BauerDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work presents an experimental dosimetric evaluation of raster-scanning particle beam delivery during simultaneous in-beam magnetic resonance (MR) imaging. Using an open MR scanner at an experimental treatment room, radiochromic film comparisons for protons, helium and carbon ions, each with and without simultaneous in-beam cine MR imaging, yielded 2D gamma pass rates ≥ 98.8 % for a 3 % / 1.5 mm criterion, and ≥ 99.9 % for 5 % / 1.5 mm. These results constitute a first experimental confirmation that time varying magnetic fields of MR gradients do not result in clinically relevant additional dose perturbations.

Indexed as

Carbon ionsHeliumIn-beam MR imagingMRIMR-integrated particle therapyOnline MR-guidanceProton

Identifiers

PMID40026908
PMCPMC11870259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.