Evidence map›Paper›PMID 40026821›Full record

ArticleBioactive materials2025

Yellow light and ultrasound Dual-responsive strontium-doped zinc oxide composites for dental caries prevention and remineralization.

Yujie Mu, Yanmei Wang, Lei Huang, Zhenzhen Weng, Tingting Zhong, Sisi Yu, Yiming Wen, Yingying Xu, Xiaolei Wang

Erratum issuedAbstract read
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In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Yujie MuSchool of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Yanmei WangThe National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Lei HuangSchool of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Zhenzhen WengSchool of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Tingting ZhongSchool of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Sisi YuThe National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Yiming WenThe National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, PR China.
Yingying XuKey Laboratory of Oral Diseases in Jiangxi Province, First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, PR China.
Xiaolei WangSchool of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi, 330088, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental caries is one of the most prevalent chronic infectious diseases, mainly due to acid production by bacteria in the plaque biofilm, leading to enamel demineralization, tooth defects and pulpitis. Most of the current treatments are invasive and do not combine restoration of dental tissues, resolution of tooth staining or prevention of dental caries. In this study, a polydopamine (PDA)-encapsulated strontium-doped zinc oxide composite (Sr-ZnO@PDA, denoted as SZ@PDA) has been developed for caries prevention and remineralization. The PDA wrapping endows SZ@PDA with a narrow energy band gap (1.78 eV), which can simultaneously respond to yellow light (YL) with favorable biosafety and ultrasound (US) with high tissue penetration. The synergistic piezo-photocatalytic action of YL and US with the enhanced catalytic efficiency can generate an appropriate amount of reactive oxygen species (ROS), thus destroying the structure of bacterial cellular membranes and decomposing pigments for caries prevention and improvement of tooth staining, respectively. In addition, strontium ions (Sr

Indexed as

AntibacterialDental caries biofilmPiezo-photocatalytic effectRemineralization

Identifiers

PMID40026821
PMCPMC11869965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.