Evidence map›Paper›PMID 40026643›Full record

ArticleHealth care science2025

Study on the Effects of National Volume-Based Procurement of Chemical Drugs on Chinese Patent Medicines: Lipid-Lowering Drugs as an Example.

Zhao Yang, Xiao Han, Pei Liang, Xiaoting Zhao, Qiyun Zhu, Hui Ye, Chao Yang, Bin Jiang

Abstract read
In one paragraph

Article in Health care science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhao YangCenter for Digital Health and Artificial Intelligence Peking University First Hospital Beijing China.
Xiao HanSchool of Public Health Shanghai Jiaotong University Shanghai China.
Pei LiangWomen and Children's Hospital of Chongqing Medical University Chongqing Health Center for Women and Children Chongqing China.ORCID 0009-0005-8703-7926
Xiaoting ZhaoSchool of Pharmaceutical Sciences Peking University Beijing China.
Qiyun ZhuRevelle College University of California San Diego San Diego California USA.
Hui YeTCM-Integrated TCM & Western Medicine Dept Peking University First Hospital Beijing China.
Chao YangCenter for Digital Health and Artificial Intelligence Peking University First Hospital Beijing China.
Bin JiangResearch Center of Public Policy Peking University Beijing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atherosclerotic cardiovascular disease remains the leading cause of death worldwide. This study aims to explore the impact of national volume-based procurement (NVBP) on Chinese patent medicines and provide evidence for improving policies and promoting rational drug use. Methods: The study was based on data from the China National Health Insurance Agency that spanned January 2019 to December 2020. Descriptive analysis was conducted using volume and expenditure as variables. Interrupted time series analysis was applied to further analyze Chinese patent medicines. Results: The unit prices of atorvastatin and rosuvastatin decreased by 25%-96%, whereas the prices of Zhibitai and Xuezhikang fluctuated slightly. The affordability is measured as the monthly expenditure on treatment divided by the daily wage. After policy implementation, the affordability of atorvastatin and rosuvastatin improved from 0.242 to 0.014 and from 0.247 to 0.019, respectively. The defined daily doses (DDDs) for atorvastatin and rosuvastatin also increased, whereas total expenditures decreased in hospitals of all levels. Both at the national level and at all levels of hospital, the policy had no significant impact on expenditures for Zhibitai and Xuezhikang and their defined daily doses. Conclusions: The NVBP saved costs in the short term by incorporating high-quality, widely used lipid-lowering drugs. Notably, the policy impacted lipid-lowering chemical drugs, whereas Chinese patent medicines remained largely unaffected. Doctors' use of Chinese patent medicines did not decline, highlighting the clinical specificity of these medicines.

Indexed as

Chinese patent medicinehealth policylipid‐lowering drugsnational volume‐based procurement

Identifiers

PMID40026643
PMCPMC11869369

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.