Evidence map›Paper›PMID 40026619›Full record

ArticleMaterials today. Bio2025

An MXene nanocomposite hydrogel for enhanced diabetic infected wound healing via photothermal antibacterial properties and bioactive molecule integration.

Xue Ou, Zhijie Yu, Xi Zheng, Le Chen, Chuanyu Pan, Dandan Li, Zhenzhen Qiao, Xiaoyuan Zheng

Erratum issuedAbstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Xue OuPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Zhijie YuPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Xi ZhengPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Le ChenPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Chuanyu PanPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Dandan LiPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Zhenzhen QiaoPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.
Xiaoyuan ZhengPharmacy Department, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Medical College, Chongqing University, Chongqing, 400014, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic wounds are a major clinical challenge due to their chronic, non-healing nature, which significantly impacts patients' quality of life. Traditional treatments often fail to effectively promote wound healing, highlighting the need for new biomaterials. In this study, we developed a composite hydrogel (KC@PF@TA) that combines the photothermal and antibacterial properties of Ti₃C₂Tx-Ag (Titanium carbide-silver) with the regenerative effects of paeoniflorin (PF). The hydrogel was optimized by adjusting the composition, crosslinking density, and the incorporation of nanoparticles, which enhanced its mechanical strength, photothermal conversion efficiency, antibacterial properties, and biocompatibility. The optimized hydrogel demonstrated enhanced cell proliferation, migration, and robust photothermal and antibacterial properties in vitro. In a diabetic murine model of

Indexed as

Diabetic woundsNanocomposite hydrogelPhotothermal antibacterialTi₃C₂Tx-AgWound healing

Identifiers

PMID40026619
PMCPMC11871482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.