Evidence map›Paper›PMID 40026613›Full record

ArticleIJID regions2025

Severe dengue-related deaths in the elderly population soared in Southern Brazil in 2024.

Alexandre Sarmento Queiroga, Danielly Alves Mendes Barbosa, Tulio de Lima Campos, Alexandre Vargas Schwarzbold, Andre M Siqueira, Richard Steiner Salvato, Gabriel Luz Wallau

Abstract read
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Leveraging probabilistic forecasts for dengue preparedness and control: The 2024 Dengue Forecasting Sprint in Brazil.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandre Sarmento QueirogaNúcleo de Bioinformática, Instituto Aggeu Magalhães (IAM), Fundação Oswaldo Cruz (Fiocruz), Recife, Brazil.
Danielly Alves Mendes BarbosaDepartamento de Entomologia, Instituto Aggeu Magalhães (IAM), Fundação Oswaldo Cruz (Fiocruz), Recife, Brazil.
Tulio de Lima CamposNúcleo de Bioinformática, Instituto Aggeu Magalhães (IAM), Fundação Oswaldo Cruz (Fiocruz), Recife, Brazil.
Alexandre Vargas SchwarzboldCentro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, Brazil.
Andre M SiqueiraDrugs for Neglected Diseases Initiative (DNDi), Rio de Janeiro, RJ, Brazil; and Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Richard Steiner SalvatoPrograma de Pós-Graduação em Biociências, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Gabriel Luz WallauNúcleo de Bioinformática, Instituto Aggeu Magalhães (IAM), Fundação Oswaldo Cruz (Fiocruz), Recife, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Dengue fever is expanding worldwide on the track of climate change. In 2024, more than 14 million cases were reported. Around 6.5 million of those were reported in Brazil alone, reaching a staggering number of around 6000 deaths. Dengue lethality in severe cases were particularly high in Rio Grande do Sul, a historically less affected state which has witnessed an increased incidence and outbreaks in the last 4 years. Design: In this report, we raised some hypotheses to explain the high lethality. Results: Rio Grande do Sul has the highest proportion of elderly individuals among all states in Brazil. This factor, associated with the immunologically naive population, low levels of awareness to detect and treat severe dengue, and the difficulties in managing elderly patients, may have contributed to this higher lethality in severe dengue. Conclusions: The expected increasing dengue incidence in the region in the subsequent years highlights the urgent need of an integrated approach to raise awareness, reduce mosquito populations, and reduce dengue burden in the region, particularly, in the most vulnerable elderly population.

Indexed as

ArbovirusIncreasing burdenVulnerability

Identifiers

PMID40026613
PMCPMC11869006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.