Evidence map›Paper›PMID 40026558›Full record

ArticleJournal of Brown hospital medicine2024

Perforated Toxic Megacolon: The Dreaded Complication in Ulcerative Colitis.

Quynh-Lan Dao, Fatmaelzahraa Hammad, Kwame Dapaah-Afriyie

Abstract readCase Reports
In one paragraph

Article in Journal of Brown hospital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Journal of bacteriology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Quynh-Lan DaoDepartment of Medicine Brown University.
Fatmaelzahraa HammadDepartment of Medicine Brown University.
Kwame Dapaah-AfriyieDepartment of Medicine Brown University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxic megacolon is a severe complication of ulcerative colitis characterized by extreme dilation of the colon, often leading to life-threatening outcomes. It typically presents with symptoms such as abdominal distension, severe pain, fever, and signs of systemic toxicity. We present a case of perforated toxic megacolon in a middle-aged woman with a new diagnosis of ulcerative colitis that was refractory to corticosteroids and biologic therapy. Early recognition and treatment are crucial to reduce morbidity and mortality associated with this potentially fatal condition.

Indexed as

inflammatory bowel diseasethumbprintingtoxic megacolonulcerative colitis

Identifiers

PMID40026558
PMCPMC11864474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.