Evidence map›Paper›PMID 40026488›Full record

ArticleFrontiers in pediatrics2025

Association of preoperative cerebral oxygenation with concurrent neurobehavioral scores in term neonates with congenital heart disease compared to healthy controls.

Nhu N Tran, Anna Miner, Eniola Adeleke, Rene Phan, Ken M Brady, Mary-Lynn Brecht, Philippe Friedlich, Geena Zhou, Vidya Rajagopalan, Bradley S Peterson and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nhu N TranInstitute for the Developing Mind, The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Anna MinerKeck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Eniola AdelekeDornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, United States.
Rene PhanDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Ken M BradyLurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Mary-Lynn BrechtSchool of Nursing, University of California, Los Angeles, CA, United States.
Philippe FriedlichFetal and Neonatal Institute, Division of Neonatology, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Geena ZhouDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Vidya RajagopalanDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Bradley S PetersonInstitute for the Developing Mind, The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Jodie K Votava-SmithDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Longitudinal Assessment of Cerebrovascular Autoregulation (CA) and Associations to Neurodevelopmental Delays in Infants and Toddlers with and without Congenital Heart Disease (CHD)K23NR019121 · NINR · CHILDREN'S HOSPITAL OF LOS ANGELES · PI TRAN, NHU · 2021 to 2023
$497k
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NINR NIH HHS K23 NR019121
6 · The paper itself

Abstract

Objective: 1st: To determine the association of cerebral oxygenation (rcSO Study design: Our secondary analysis included 137 neonates (74 with CHD and 63 healthy controls). We used linear regression models to examine the association of the predictors (i.e., cerebral oxygenation, FTOE, type and severity of CHD) with the percentage of abnormal neurobehavioral scores (outcome). The models included the main effects of group, rcSO Results: Neonates with CHD had lower rcSO Conclusions: The CHD and healthy neonates had significantly different associations of both rcSO

Indexed as

cerebral oxygenationcerebral oxygen extractioncongenital heart diseaseneonatesneurobehaviorneurodevelopmental outcome

Identifiers

PMID40026488
PMCPMC11868078

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.