ArticleJournal of preventive medicine and hygiene2024
Global Disparities in Colorectal Cancer: Unveiling the Present Landscape of Incidence and Mortality Rates, Analyzing Geographical Variances, and Assessing the Human Development Index.
Article in Journal of preventive medicine and hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Screening of known gut microbiome-derived metabolites in anti-tumor immunity of colorectal cancer.Journal for immunotherapy of cancer · 2026Article
- Metabolic Alterations in Blood and Saliva During the First Two Cycles of Adjuvant Chemotherapy Correlate with 5-FU Dose Reduction Requirement in Patients with Colorectal Cancer.European journal of drug metabolism and pharmacokinetics · 2026Article
- Temporal Trends in Colorectal Cancer Associated With Type 2 Diabetes Mellitus in U.S. Adults, 1999-2023: A CDC Wonder Database Analysis-A Population-Based Cross-Sectional Study.Health science reports · 2026Article
- Colorectal Cancer Mortality Following an Organized Fecal Immunochemical Test-Based Screening Program.JAMA network open · 2026Article
- DCP-TS: A Unified Spatiotemporal Framework for Real-Time Desmoking and Flicker Suppression in Laparoscopic Surgical Videos.Bioengineering (Basel, Switzerland) · 2026Article
- Evolving therapeutics in colorectal cancer peritoneal metastases.Cancer metastasis reviews · 2026Review
- Implication of Epigenetic Alterations of ZEB1 in Colorectal Cancer (CRC) Pathogenesis and Therapy Development.Current issues in molecular biology · 2026Review
- Perioperative characteristics and outcomes of colorectal cancer in elderly patients.World journal of gastrointestinal surgery · 2026Article
- Global, regional and national burden of colorectal cancer attributable to low-fiber diet from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.Frontiers in nutrition · 2026Article
- Investigating the Therapeutic Potential of Cisplatin- and Rutin-Loaded Nanoliposomes against Colorectal Cancer Cells.Anti-cancer agents in medicinal chemistry · 2026Article
- Evolution or Revolution in Colorectal Cancer Treatment: Present and Future of New Therapeutic Options. A Narrative Review.Oncology research · 2026Review
- Spatial patterns, temporal trends, and age-period-cohort effects of colon cancer incidence in Kazakhstan, 2005-2024.Frontiers in oncology · 2026Article
- IDF-Net: Interpretable Dynamic Fusion Network for Colorectal Cancer Diagnosis Using Cross-Modal Imaging.Diagnostics (Basel, Switzerland) · 2025Article
- Prognostic Factors and Biomarker Performance in Patients with Colorectal Cancer Receiving Reduced-Dose 5-Fluorouracil Therapy: A Retrospective Cohort Analysis.Journal of clinical medicine · 2025Article
- Molecular Basis, Diagnostic Approaches, and Therapeutic Strategies in Colorectal Cancer-Comprehensive Review.International journal of molecular sciences · 2025Review
- Genomic characterization of patients with colorectal cancer.Hereditary cancer in clinical practice · 2025Article
- Effect of hydrocolloid dressing combined with continuous nursing intervention on patients with permanent ostomy.BMC surgery · 2025Article
- Safety and Efficacy of Serplulimab Combined with Neoadjuvant Chemoradiotherapy in High-Risk Locally Advanced Rectal Cancer: A Retrospective Study.Cancer management and research · 2025Article
- Association between the Human Development Index and the burden of major gastrointestinal cancers: results from Global Burden of Disease 2021.Gastroenterology and hepatology from bed to bench · 2025Article
- Temporal trends in colorectal cancer mortality in Greece, 2014-2022: a Joinpoint regression analysis.Annals of gastroenterologyArticle
Corrections and comments
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3 authors.
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Abstract
Background: Colorectal cancer poses a major global health threat, with increasing incidence and mortality rates worldwide. This study examined the incidence and mortality rates of colorectal cancer globally in 2020 and explored the relationship with the Human Development Index (HDI). Material and methods: This research utilizes data from the International Agency for Research on Cancer's (IARC) GLOBOCAN 2020 project, an esteemed source of up-to-date international cancer statistics. Age-standardized incidence rates (ASIR) and age-standardized mortality rates (ASMR) per 100,000 individuals were calculated. The association between ASIR, ASMR, and the HDI was analyzed using Pearson correlation, considering a statistical significance threshold of p < 0.05. Results: In 2020, a total of 1,931,590 new colorectal cancer cases were recorded globally, with a male predominance of 55.18%. The global colorectal cancer ASIR was 19.5 per 100,000 (23.4 in males, 16.2 in females). Furthermore, there were 935,173 colorectal cancer-related mortality, with males accounting for 55.13%. The overall colorectal cancer ASMR was 9 (11 in males, 7.2 in females). A strong positive correlation emerged between ASIR and ASMR (0.895, p ≤ 0.001), HDI (0.794, p ≤ 0.001), life expectancy (0.724, p ≤ 0.001), education (0.743, p ≤ 0.001), and income (0.706, p ≤ 0.001). Similarly, positive correlations were also found between ASMR and HDI (0.638, p ≤ 0.001), life expectancy (0.569, p ≤ 0.001), education (0.631, p ≤ 0.001), and income (0.512, p ≤ 0.001). Conclusions: This global analysis highlights rising colorectal cancer incidence and mortality as a major public health threat worldwide. The findings reveal a positive association between a country's development level, as measured by HDI, and colorectal cancer incidence and mortality.
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